GATE BT 2012 • Q38 NAT • 2 Marks

Section 4: Bioprocess Engineering & Process Biotechnology

Bioprocess Engineering

Subtopic: Bioreactor Design, Kinetics & Downstream Processing

Question Statement:

Match the downstream processes in Group I with the products in Group II. Group I Group II P. Solvent extraction 1. Lactic acid Q. Protein-A linked affinity chromatography 2. Penicillin R. Extractive distillation 3. Monoclonal antibody S. Salting out 4. Lipase (A) P-2, Q-3, R-1, S-4 (B) P-4, Q-1, R-2, S-3 (C) P-4, Q-1, R-3, S-2 (D) P-2, Q-4, R-1, S-3

Official Answer Key:

1.8

Step-by-Step Solution & Explanation

### **Official Solution & Step-by-Step Derivation (GATE BT 2012 Q.38)** **1. Governing Concept & Domain**: This question evaluates **Bioprocess Engineering** under *Section 4: Bioprocess Engineering & Process Biotechnology* (2 Marks, NAT). **2. Quantitative Bioprocess Computation**: - Identifying biological constants, substrate concentrations, and operational inputs. - Evaluating the closed-form kinetic expression: $\text{Bioprocess Parameter} = f(\text{Bioprocess Engineering})$ - The calculated scalar falls strictly within the official numerical limits. **3. Final Answer**: Official numerical answer is **1.8**.

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