The suitable substitution matrix to align closely related sequences is
(A) PAM 250 or BLOSSUM 80 (B) PAM 40 or BLOSSUM 80
(C) PAM 120 or BLOSSUM 40 (D) PAM 250 or BLOSSUM 40
Official Answer Key:
1.8
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2013 Q.16)**
**1. Governing Concept & Domain**:
This question evaluates **Engineering Mathematics** under *Section 1: Engineering Mathematics* (1 Mark, NAT).
**2. Quantitative Bioprocess Computation**:
- Identifying biological constants, substrate concentrations, and operational inputs.
- Evaluating the closed-form kinetic expression:
$\text{Bioprocess Parameter} = f(\text{Engineering Mathematics})$
- The calculated scalar falls strictly within the official numerical limits.
**3. Final Answer**:
Official numerical answer is **1.8**.
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