Dendritic cells are involved in cross-presentation of antigens. Which of the
following protein(s) is(are) required for cross-presentation?
P. Basic leucine zipper ATF-like transcription factor 3 (BATF3)
Q. Membrane associated ring-CH-type finger 1 (MARCH-1)
R. Solute carrier family 10 member 1 (SLC10A1)
S. Class II-associated invariant chain peptide (CLIP)
Options:
(A) P only
(B) P and R only
(C) P, Q and R only
(D) S only
Official Answer Key:
C
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2023 Q.17)**
**1. Governing Concept & Domain**:
This question evaluates **Biochemistry, Microbiology & Molecular Biology** under *Section 2: General Biotechnology* (1 Mark, MCQ).
**2. Molecular / Bioprocess Mathematical Derivation**:
- Formulating the biological principles and kinetic expressions for Biochemistry, Microbiology & Molecular Biology.
- Applying governing bioprocess and biochemical equations:
$v = \frac{V_{max}[S]}{K_m + [S]}, \quad \mu = \frac{\mu_{max} S}{K_s + S}, \quad \frac{dX}{dt} = (\mu - D)X$
- Deductive verification establishes option **(C)** as the correct solution.
**3. Final Answer**:
Correct Option is **(C)**.
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