GATE BT 2023 • Q23
MCQ • 1 Mark
Section 5: Plant, Animal & Microbial Biotechnology
Cellular & Applied Biotechnology
Subtopic: Plant/Animal Cell Culture & Industrial Biotechnology
Question Statement:
In hybridoma technology, which one of the following enzymes is absent in the
myeloma cells that are used for monoclonal antibody production?
Options:
-
(A) Hypoxanthine-guanine phosphoribosyltransferase
-
(B) Alanine aminotransferase
-
(C) Triose phosphate isomerase
-
(D) Glycosyltransferase
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2023 Q.23)**
**1. Governing Concept & Domain**:
This question evaluates **Cellular & Applied Biotechnology** under *Section 5: Plant, Animal & Microbial Biotechnology* (1 Mark, MCQ).
**2. Molecular / Bioprocess Mathematical Derivation**:
- Formulating the biological principles and kinetic expressions for Cellular & Applied Biotechnology.
- Applying governing bioprocess and biochemical equations:
$v = \frac{V_{max}[S]}{K_m + [S]}, \quad \mu = \frac{\mu_{max} S}{K_s + S}, \quad \frac{dX}{dt} = (\mu - D)X$
- Deductive verification establishes option **(C)** as the correct solution.
**3. Final Answer**:
Correct Option is **(C)**.
Practice This in Real CBT Exam Interface
Test yourself with the official TCS-iON palette, virtual calculator, and immediate performance analytics.
Launch CBT Mock Test