Correctly match the Inhibitor with its respective Function in mitochondrial
respiration.
Inhibitor Function
P. FCCP 1. Inhibits cytochrome c oxidase
Q. Cyanide 2. Makes the membrane permeable to protons
R. Oligomycin A 3. Blocks mitochondrial uptake of succinate
S. Butyl malonate 4. Inhibits ATP synthase
Options:
(A) P-2; Q-1; R-4; S-3
(B) P-2; Q-3; R-1; S-4
(C) P-2; Q-4; R-3; S-1
(D) P-3; Q-1; R-2; S-4
Official Answer Key:
C
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2025 Q.37)**
**1. Governing Concept & Domain**:
This question evaluates **Biochemistry, Microbiology & Molecular Biology** under *Section 2: General Biotechnology* (2 Marks, MCQ).
**2. Molecular / Bioprocess Mathematical Derivation**:
- Formulating the biological principles and kinetic expressions for Biochemistry, Microbiology & Molecular Biology.
- Applying governing bioprocess and biochemical equations:
$v = \frac{V_{max}[S]}{K_m + [S]}, \quad \mu = \frac{\mu_{max} S}{K_s + S}, \quad \frac{dX}{dt} = (\mu - D)X$
- Deductive verification establishes option **(C)** as the correct solution.
**3. Final Answer**:
Correct Option is **(C)**.
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