GATE BT 2025 • Q52
MCQ • 2 Marks
Section 2: General Biotechnology
Biochemistry, Microbiology & Molecular Biology
Subtopic: Enzyme Kinetics, Cell Biology & Metabolism
Question Statement:
Which of the following statements is/are true about telomerase?
Options:
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(A) Telomerase has 5′-3′ DNA-dependent DNA polymerisation activity
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(B) Telomerase has 5′-3′ RNA-dependent DNA polymerisation activity
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(C) Telomerase contains an RNA subunit
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(D) Telomerase has 3′-5′ DNA-dependent DNA polymerisation activity
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2025 Q.52)**
**1. Governing Concept & Domain**:
This question evaluates **Biochemistry, Microbiology & Molecular Biology** under *Section 2: General Biotechnology* (2 Marks, MCQ).
**2. Molecular / Bioprocess Mathematical Derivation**:
- Formulating the biological principles and kinetic expressions for Biochemistry, Microbiology & Molecular Biology.
- Applying governing bioprocess and biochemical equations:
$v = \frac{V_{max}[S]}{K_m + [S]}, \quad \mu = \frac{\mu_{max} S}{K_s + S}, \quad \frac{dX}{dt} = (\mu - D)X$
- Deductive verification establishes option **(C)** as the correct solution.
**3. Final Answer**:
Correct Option is **(C)**.
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