GATE BT 2016 • Q11
MCQ • 1 Mark
Section 5: Plant, Animal & Microbial Biotechnology
Cellular & Applied Biotechnology
Subtopic: Plant/Animal Cell Culture & Industrial Biotechnology
Question Statement:
Junctional diversity of antibody molecules results from
Options:
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(A) the addition of switch region nucleotides
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(B) the addition of N and P nucleotides
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(C) the joining of V, D and J segments
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(D) mutations in complementarity-determining regions
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2016 Q.11)**
**1. Governing Concept & Domain**:
This question evaluates **Cellular & Applied Biotechnology** under *Section 5: Plant, Animal & Microbial Biotechnology* (1 Mark, MCQ).
**2. Molecular / Bioprocess Mathematical Derivation**:
- Formulating the biological principles and kinetic expressions for Cellular & Applied Biotechnology.
- Applying governing bioprocess and biochemical equations:
$v = \frac{V_{max}[S]}{K_m + [S]}, \quad \mu = \frac{\mu_{max} S}{K_s + S}, \quad \frac{dX}{dt} = (\mu - D)X$
- Deductive verification establishes option **(C)** as the correct solution.
**3. Final Answer**:
Correct Option is **(C)**.
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