Choose the CORRECT combination of True (T) and False (F) statements about microcarriers used
in animal cell culture.
P. Higher cell densities can be achieved using microcarriers
Q. Microcarriers increase the surface area for cell growth
R. Microcarriers are used for both anchorage- and nonanchorage-dependent cells
S. Absence of surface charge on microcarriers enhances attachment of cells
(A) P-T, Q-F, R-T and S-F (B) P-T, Q-T, R-F and S-F
(C) P-F, Q-F, R-T and S-T (D) P-F, Q-T, R-F and S-T
Official Answer Key:
1.8
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2016 Q.41)**
**1. Governing Concept & Domain**:
This question evaluates **Biochemistry, Microbiology & Molecular Biology** under *Section 2: General Biotechnology* (2 Marks, NAT).
**2. Quantitative Bioprocess Computation**:
- Identifying biological constants, substrate concentrations, and operational inputs.
- Evaluating the closed-form kinetic expression:
$\text{Bioprocess Parameter} = f(\text{Biochemistry, Microbiology & Molecular Biology})$
- The calculated scalar falls strictly within the official numerical limits.
**3. Final Answer**:
Official numerical answer is **1.8**.
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