Question Statement:
A pedigree of an inheritable disease is shown below.
What type of inheritance does the disease follow?
(A) Autosomal dominant (B) X-linked dominant
(C) X-linked recessive (D) Autosomal recessive
/Artifact <</Attached [/Top ]/Subtype /Header /Type /Pagination >>BDC
BT
/GS0 gs
/TT0 8.04 Tf
54 798.36 Td
[(G)5.995 (A)6.007 (T)13.993 (E )-3.993 (2)-6.007 (0)7.002 (1)-5.995 (8)7.002 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )2.45 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-3.01 ( )10.995 ( )-2.985 ( )-3.01 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-3.01 ( )-2.985 ( )10.983 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-3.01 ( )10.995 ( )-2.985 ( )-3.01 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )-52.04 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-3.01 ( )11.007 ( )-3.01 ( )-2.985 ( )10.995 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )10.995 ( )-3.01 ( )-2.985 ( )-3.01 ( )10.995 ( )-2.998 ( )-19.192 (B)-3.993 (i)-5 (o)6.99 (t)-5 (e)11.007 (c)10.995 (h)-5.995 (n)-6.007 (o)7.002 (l)9.005 (o)7.002 (g)-6.007 (y)3.321 ( )]TJ
ET
52.56 795 490.44 0.48 re
f*
EMC
/Artifact <</Attached [/Bottom ]/Subtype /Footer /Type /Pagination >>BDC
BT
0.0373 Tc 54 37.824Tj
0 Tc 10.224 0 Td
( )Tj
ET
52.56 46.104 317.95 0.48 re
f*
q
369.08 35.79 172.01 9.12 re
W* n
BT
526.78 37.704 Td
(9)Tj
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369.08 35.79 172.01 9.12 re
W* n
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530.86 37.704 Td
(/)Tj
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369.08 35.79 172.01 9.12 re
W* n
BT
0.06 Tc 533.02 37.704 Td
(12)Tj
ET
Q
q
369.08 35.79 172.01 9.12 re
W* n
BT
541.08 37.704 Td
( )Tj
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EMC
Q
q
59.4 625.17 33.99 162.51 re
W* n
/P <</MCID 0 >>BDC
q
59.4 625.18 33.984 162.5 re
W* n
BT
/TT0 12 Tf
64.824 776.88 Td
(Q.39)Tj
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59.4 625.18 33.984 162.5 re
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/TT1 12 Tf
88.464 776.88 Td
( )Tj
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59.4 625.18 33.984 162.5 re
W* n
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/TT0 12 Tf
100.82 776.88 Td
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/P <</MCID 1 >>BDC
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93.39 663.46 452.13 124.22 re
W* n
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/TT0 12 Tf
99.144 776.88 Td
[(Ma)3 (tch )-227 (the )]TJ
ET
Q
q
93.39 663.46 452.13 124.22 re
W* n
BT
/TT0 12 Tf
155.9 776.88 Td
[(indus)-2 (tria)3 (l )]TJ
ET
Q
q
93.39 663.46 452.13 124.22 re
W* n
BT
/TT0 12 Tf
207.05 776.88 Td
[(pr)-6 (oduc)4 (ts )-232 (mentioned )-227 (in )-231 (Gr)-4 (oup )-239 (I)13 ( )-229 (with )-231 (their)3 ( )-229 (produ)-6 (c)-5 (e)4 (r )-226 (or)-6 (ga)4 (nism)-4 (s )-230 (in)8 ( )]TJ
ET
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93.39 663.46 452.13 124.22 re
W* n
BT
/TT0 12 Tf
542.76 776.88 Td
( )Tj
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93.39 663.46 452.13 124.22 re
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BT
/TT0 12 Tf
99.144 763.08 Td
[(Gr)5 (oup )-9 (II)]TJ
ET
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93.39 663.46 452.13 124.22 re
W* n
BT
/TT0 12 Tf
140.78 763.08 Td
( )Tj
ET
EMC
Q
/P <</MCID 2 >>BDC
q
93.39 663.45 452.13 124.23 re
W* n
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/TT0 12 Tf
99.144 749.26 Td
( )Tj
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/P <</MCID 3 >>BDC
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93.39 663.45 452.13 124.23 re
W* n
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/TT2 12 Tf
99.144 735.22 Td
[(G)8 (r)4 (ou)-3 (p)-3 ( I)]TJ
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93.39 663.45 452.13 124.23 re
W* n
BT
/TT2 12 Tf
140.78 735.22 Td
( )Tj
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93.39 663.45 452.13 124.23 re
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/TT2 12 Tf
171.14 735.22 Td
( )Tj
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93.39 663.45 452.13 124.23 re
W* n
BT
/TT2 12 Tf
201.17 735.22 Td
[(G)8 (r)4 (ou)-3 (p)-3 ( II)]TJ
ET
Q
q
93.39 663.45 452.13 124.23 re
W* n
BT
/TT2 12 Tf
247.49 735.22 Td
( )Tj
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EMC
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/P <</MCID 4 >>BDC
q
93.39 663.45 452.13 124.23 re
W* n
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/TT0 12 Tf
0.048 Tc 99.144 721.66 Td
(P.)Tj
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93.39 663.45 452.13 124.23 re
W* n
BT
/TT0 12 Tf
108.86 721.66 Td
( )Tj
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q
93.39 663.45 452.13 124.23 re
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BT
/TT0 12 Tf
111.86 721.66 Td
( )Tj
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Q
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93.39 663.45 452.13 124.23 re
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/TT0 12 Tf
114.86 721.66 Td
[(C)-2 (it)-3 (ric)5 ( a)4 (c)4 (id)]TJ
ET
Q
q
93.39 663.45 452.13 124.23 re
W* n
BT
/TT0 12 Tf
165.14 721.66 Td
( )Tj
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93.39 663.45 452.13 124.23 re
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/TT0 12 Tf
171.14 721.66 Td
( )Tj
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93.39 663.45 452.13 124.23 re
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BT
/TT0 12 Tf
201.17 721.66 Td
(1)Tj
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93.39 663.45 452.13 124.23 re
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BT
/TT0 12 Tf
207.17 721.66 Td
(. )Tj
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93.39 663.45 452.13 124.23 re
W* n
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/TT3 12 Tf
213.17 721.66 Td
[(T)-3 (richode)5 (rma v)5 (iri)-4 (de)]TJ
ET
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93.39 663.45 452.13 124.23 re
W* n
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/TT0 12 Tf
306.79 721.66 Td
( )Tj
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EMC
Q
/P <</MCID 5 >>BDC
q
93.39 663.45 452.13 124.23 re
W* n
BT
/TT0 12 Tf
99.144 707.86 Td
[(Q. Cellul)-2 (a)4 (se)]TJ
ET
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93.39 663.45 452.13 124.23 re
W* n
BT
/TT0 12 Tf
158.42 707.86 Td
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93.39 663.45 452.13 124.23 re
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/TT0 12 Tf
171.14 707.86 Td
( )Tj
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93.39 663.45 452.13 124.23 re
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/TT0 12 Tf
201.17 707.86 Td
(2)Tj
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93.39 663.45 452.13 124.23 re
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/TT0 12 Tf
207.17 707.86 Td
(. )Tj
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93.39 663.45 452.13 124.23 re
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/TT3 12 Tf
213.17 707.86 Td
[(C)-2 (lost)-4 (ridi)-4 (um ac)6 (e)4 (tobut)-3 (y)4 (li)-3 (c)4 (um)]TJ
ET
Q
q
93.39 663.45 452.13 124.23 re
W* n
BT
/TT0 12 Tf
346.87 707.86 Td
( )Tj
ET
EMC
Q
/P <</MCID 6 >>BDC
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93.39 663.45 452.13 124.23 re
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/TT0 12 Tf
99.144 694.06 Td
[(R)-2 (. Vitamin B)]TJ
ET
Q
q
93.39 663.45 452.13 124.23 re
W* n
BT
163.46 693.1 Td
[(1)-5.995 (2)-6.007 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )]TJ
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93.39 663.45 452.13 124.23 re
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/TT0 12 Tf
201.65 694.06 Td
(3.)Tj
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93.39 663.45 452.13 124.23 re
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/TT0 12 Tf
210.65 694.06 Td
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93.39 663.45 452.13 124.23 re
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/TT3 12 Tf
213.65 694.06 Td
[(A)11 (spe)3 (rgil)-4 (lus ni)-4 (ge)4 (r)]TJ
ET
Q
q
93.39 663.45 452.13 124.23 re
W* n
BT
/TT0 12 Tf
296.57 694.06 Td
( )Tj
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EMC
Q
/P <</MCID 7 >>BDC
q
93.39 663.45 452.13 124.23 re
W* n
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/TT0 12 Tf
0.048 Tc 99.144 680.26 Td
(S.)Tj
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q
93.39 663.45 452.13 124.23 re
W* n
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/TT0 12 Tf
108.86 680.26 Td
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93.39 663.45 452.13 124.23 re
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/TT0 12 Tf
111.86 680.26 Td
( )Tj
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93.39 663.45 452.13 124.23 re
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/TT0 12 Tf
114.86 680.26 Td
[(B)7 (utanol)]TJ
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93.39 663.45 452.13 124.23 re
W* n
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/TT0 12 Tf
152.78 680.26 Td
( )Tj
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93.39 663.45 452.13 124.23 re
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/TT0 12 Tf
171.14 680.26 Td
( )Tj
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93.39 663.45 452.13 124.23 re
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/TT0 12 Tf
201.17 680.26 Td
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93.39 663.45 452.13 124.23 re
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/TT0 12 Tf
207.17 680.26 Td
(. )Tj
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q
93.39 663.45 452.13 124.23 re
W* n
BT
/TT3 12 Tf
213.17 680.26 Td
[(Propioni)-3 (bac)4 (terium freude)6 (nre)3 (ichii)]TJ
ET
Q
q
93.39 663.45 452.13 124.23 re
W* n
BT
/TT0 12 Tf
375.55 680.26 Td
( )Tj
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EMC
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/P <</MCID 8 >>BDC
q
93.39 663.45 452.13 124.23 re
W* n
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/TT0 12 Tf
99.144 666.46 Td
( )Tj
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EMC
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93.39 642.21 212.57 14.04 re
W* n
/P <</MCID 9 >>BDC
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93.384 642.22 212.57 14.04 re
W* n
BT
/TT0 12 Tf
98.784 645.46 Td
[(\(A)5 (\) P)]TJ
ET
Q
q
93.384 642.22 212.57 14.04 re
W* n
BT
/TT0 12 Tf
125.06 645.46 Td
(-)Tj
ET
Q
q
93.384 642.22 212.57 14.04 re
W* n
BT
/TT0 12 Tf
129.02 645.46 Td
(4)Tj
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q
93.384 642.22 212.57 14.04 re
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/TT0 12 Tf
135.02 645.46 Td
(, Q)Tj
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93.384 642.22 212.57 14.04 re
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/TT0 12 Tf
149.66 645.46 Td
(-)Tj
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93.384 642.22 212.57 14.04 re
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/TT0 12 Tf
153.62 645.46 Td
(3)Tj
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93.384 642.22 212.57 14.04 re
W* n
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/TT0 12 Tf
159.62 645.46 Td
(, R)Tj
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93.384 642.22 212.57 14.04 re
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/TT0 12 Tf
173.66 645.46 Td
(-)Tj
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93.384 642.22 212.57 14.04 re
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/TT0 12 Tf
177.62 645.46 Td
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93.384 642.22 212.57 14.04 re
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/TT0 12 Tf
183.65 645.46 Td
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93.384 642.22 212.57 14.04 re
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/TT0 12 Tf
196.37 645.46 Td
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93.384 642.22 212.57 14.04 re
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/TT0 12 Tf
200.33 645.46 Td
(2)Tj
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93.384 642.22 212.57 14.04 re
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/TT0 12 Tf
206.45 645.46 Td
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305.96 642.21 239.57 14.04 re
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311.35 645.46 Td
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305.95 642.22 239.57 14.04 re
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/TT0 12 Tf
315.31 645.46 Td
[(B)7 (\) P)]TJ
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305.95 642.22 239.57 14.04 re
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/TT0 12 Tf
336.91 645.46 Td
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305.95 642.22 239.57 14.04 re
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/TT0 12 Tf
340.87 645.46 Td
(3)Tj
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305.95 642.22 239.57 14.04 re
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/TT0 12 Tf
346.87 645.46 Td
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305.95 642.22 239.57 14.04 re
W* n
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/TT0 12 Tf
361.63 645.46 Td
(-)Tj
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305.95 642.22 239.57 14.04 re
W* n
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/TT0 12 Tf
365.59 645.46 Td
(1)Tj
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305.95 642.22 239.57 14.04 re
W* n
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/TT0 12 Tf
371.59 645.46 Td
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305.95 642.22 239.57 14.04 re
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/TT0 12 Tf
385.63 645.46 Td
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305.95 642.22 239.57 14.04 re
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/TT0 12 Tf
389.59 645.46 Td
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305.95 642.22 239.57 14.04 re
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/TT0 12 Tf
395.59 645.46 Td
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305.95 642.22 239.57 14.04 re
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/TT0 12 Tf
408.31 645.46 Td
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305.95 642.22 239.57 14.04 re
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412.27 645.46 Td
(4)Tj
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305.95 642.22 239.57 14.04 re
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/TT0 12 Tf
418.39 645.46 Td
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EMC
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93.39 625.17 212.57 17.04 re
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98.784 631.42 Td
(\(C\) P)Tj
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93.384 625.18 212.57 17.04 re
W* n
BT
/TT0 12 Tf
124.46 631.42 Td
(-)Tj
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93.384 625.18 212.57 17.04 re
W* n
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/TT0 12 Tf
128.42 631.42 Td
(2, Q)Tj
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q
93.384 625.18 212.57 17.04 re
W* n
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/TT0 12 Tf
149.06 631.42 Td
(-)Tj
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93.384 625.18 212.57 17.04 re
W* n
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/TT0 12 Tf
153.02 631.42 Td
(1, R)Tj
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q
93.384 625.18 212.57 17.04 re
W* n
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/TT0 12 Tf
173.06 631.42 Td
(-)Tj
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q
93.384 625.18 212.57 17.04 re
W* n
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/TT0 12 Tf
177.02 631.42 Td
(4)Tj
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93.384 625.18 212.57 17.04 re
W* n
BT
/TT0 12 Tf
183.05 631.42 Td
(, S)Tj
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93.384 625.18 212.57 17.04 re
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195.77 631.42 Td
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93.384 625.18 212.57 17.04 re
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/TT0 12 Tf
199.73 631.42 Td
(3)Tj
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93.384 625.18 212.57 17.04 re
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/TT0 12 Tf
205.85 631.42 Td
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EMC
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305.96 625.17 239.57 17.04 re
W* n
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q
305.95 625.18 239.57 17.04 re
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311.35 631.42 Td
[(\(D)5 (\) P)]TJ
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305.95 625.18 239.57 17.04 re
W* n
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/TT0 12 Tf
337.63 631.42 Td
(-)Tj
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305.95 625.18 239.57 17.04 re
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/TT0 12 Tf
341.59 631.42 Td
(3, Q)Tj
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305.95 625.18 239.57 17.04 re
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/TT0 12 Tf
362.23 631.42 Td
(-)Tj
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305.95 625.18 239.57 17.04 re
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/TT0 12 Tf
366.19 631.42 Td
(1)Tj
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305.95 625.18 239.57 17.04 re
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/TT0 12 Tf
372.19 631.42 Td
(, R)Tj
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305.95 625.18 239.57 17.04 re
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/TT0 12 Tf
386.23 631.42 Td
(-)Tj
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305.95 625.18 239.57 17.04 re
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/TT0 12 Tf
390.19 631.42 Td
(4)Tj
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305.95 625.18 239.57 17.04 re
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/TT0 12 Tf
396.19 631.42 Td
(, S)Tj
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305.95 625.18 239.57 17.04 re
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/TT0 12 Tf
408.91 631.42 Td
(-)Tj
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305.95 625.18 239.57 17.04 re
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/TT0 12 Tf
412.87 631.42 Td
(2)Tj
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305.95 625.18 239.57 17.04 re
W* n
BT
/TT0 12 Tf
419.02 631.42 Td
( )Tj
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EMC
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Q
BT
/P <</MCID 13 >>BDC
/TT0 12 Tf
54 614.38 Td
( )Tj
EMC
/P <</MCID 14 >>BDC
0 -13.8 Td
( )Tj
EMC
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q
59.4 445.75 33.99 151.82 re
W* n
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59.4 445.75 33.984 151.82 re
W* n
BT
64.824 586.78 Td
(Q.40)Tj
ET
Q
q
59.4 445.75 33.984 151.82 re
W* n
BT
/TT1 12 Tf
88.464 586.78 Td
( )Tj
ET
Q
q
59.4 445.75 33.984 151.82 re
W* n
BT
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( )Tj
ET
EMC
Q
Q
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q
93.39 483.55 452.13 114.01 re
W* n
BT
99.144 585.82 Td
(5)Tj
ET
Q
q
93.39 483.55 452.13 114.01 re
W* n
BT
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105.14 585.82 Td
<0063>Tj
ET
Q
q
93.39 483.55 452.13 114.01 re
W* n
BT
108.14 585.82 Td
<20>Tj
ET
Q
q
93.39 483.55 452.13 114.01 re
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BT
111.14 585.82 Td
[<63>4 <61>4 <7070696E67>8 <206F>-9 <66206D524E41207472>3 <61>4 <6E>-9 <7363>3 <726970747320>]TJ
ET
Q
q
93.39 483.55 452.13 114.01 re
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BT
255.77 585.82 Td
[<696E2065756B61>6 <72>-16 <79>20 <6F74657320>]TJ
ET
Q
q
93.39 483.55 452.13 114.01 re
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BT
322.99 585.82 Td
[<696E76>-11 <6F6C7665>]TJ
ET
Q
q
93.39 483.55 452.13 114.01 re
W* n
BT
359.11 585.82 Td
<73>Tj
ET
Q
q
93.39 483.55 452.13 114.01 re
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BT
363.79 585.82 Td
<20>Tj
ET
Q
q
93.39 483.55 452.13 114.01 re
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BT
366.79 585.82 Td
[<7468652066>5 <6F6C6C>-3 <6F77696E67>10 <20>-9 <65>4 <7665>4 <6E74>-11 <733A>]TJ
ET
Q
q
93.39 483.55 452.13 114.01 re
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BT
468.22 585.82 Td
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ET
EMC
Q
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q
93.39 483.55 452.13 114.01 re
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BT
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EMC
Q
/P <</MCID 18 >>BDC
q
93.39 483.55 452.13 114.01 re
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BT
99.144 557.23 Td
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ET
Q
q
93.39 483.55 452.13 114.01 re
W* n
BT
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238.13 557.23 Td
<0063>Tj
ET
Q
q
93.39 483.55 452.13 114.01 re
W* n
BT
241.13 557.23 Td
<20>Tj
ET
Q
q
93.39 483.55 452.13 114.01 re
W* n
BT
244.13 557.23 Td
[<65>4 <6E64>]TJ
ET
Q
q
93.39 483.55 452.13 114.01 re
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BT
261.53 557.23 Td
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ET
EMC
Q
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q
93.39 483.55 452.13 114.01 re
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BT
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[<512E2052656D6F7661>5 <6C206F6620>]TJ
ET
Q
q
93.39 483.55 452.13 114.01 re
W* n
BT
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173.06 542.59 Td
<004A>Tj
ET
Q
q
93.39 483.55 452.13 114.01 re
W* n
BT
177.98 542.59 Td
<2D>Tj
ET
Q
q
93.39 483.55 452.13 114.01 re
W* n
BT
181.97 542.59 Td
[<70686F737068>-10 <61>4 <7465206F66>5 <20746865207472>3 <6970686F73>-2 <706861>4 <7465206F6E>-7 <20666972>4 <73742062617365>4 <2061>4 <742074>-3 <6865>4 <2035>]TJ
ET
Q
q
93.39 483.55 452.13 114.01 re
W* n
BT
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423.58 542.59 Td
<0063>Tj
ET
Q
q
93.39 483.55 452.13 114.01 re
W* n
BT
426.58 542.59 Td
<20>Tj
ET
Q
q
93.39 483.55 452.13 114.01 re
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BT
429.58 542.59 Td
[<65>4 <6E64>]TJ
ET
Q
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93.39 483.55 452.13 114.01 re
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BT
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EMC
Q
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q
93.39 483.55 452.13 114.01 re
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BT
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[<52>-2 <2E2035>]TJ
ET
Q
q
93.39 483.55 452.13 114.01 re
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119.18 527.83 Td
<0063>Tj
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Q
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93.39 483.55 452.13 114.01 re
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BT
122.18 527.83 Td
<2D>Tj
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93.39 483.55 452.13 114.01 re
W* n
BT
126.14 527.83 Td
<35>Tj
ET
Q
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93.39 483.55 452.13 114.01 re
W* n
BT
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132.14 527.83 Td
<0063>Tj
ET
Q
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93.39 483.55 452.13 114.01 re
W* n
BT
135.14 527.83 Td
<20>Tj
ET
Q
q
93.39 483.55 452.13 114.01 re
W* n
BT
138.14 527.83 Td
[<6C69>-3 <6E6B61>4 <67>10 <65>4 <206265>4 <74>]TJ
ET
Q
q
93.39 483.55 452.13 114.01 re
W* n
BT
190.97 527.83 Td
[<77>-7 <65>4 <65>4 <6E20>-9 <474D5020616E6420746865>3 <20666972>4 <73742062617365>4 <20>-9 <61>4 <742035>]TJ
ET
Q
q
93.39 483.55 452.13 114.01 re
W* n
BT
/C0_0 12 Tf
350.71 527.83 Td
<0063>Tj
ET
Q
q
93.39 483.55 452.13 114.01 re
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BT
353.71 527.83 Td
<20>Tj
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Q
q
93.39 483.55 452.13 114.01 re
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BT
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[<65>4 <6E64>]TJ
ET
Q
q
93.39 483.55 452.13 114.01 re
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BT
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ET
EMC
Q
/P <</MCID 21 >>BDC
q
93.39 483.55 452.13 114.01 re
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BT
99.144 514.15 Td
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Q
q
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EMC
Q
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93.39 483.55 452.13 114.01 re
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EMC
Q
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q
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EMC
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q
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q
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[<2841>5 <2920502C20512C20522C2053>]TJ
ET
Q
q
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BT
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EMC
Q
Q
q
305.96 462.31 239.57 14.04 re
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q
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[<2842>10 <2920502C2052>-3 <2C20512C2053>]TJ
ET
Q
q
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ET
EMC
Q
Q
q
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q
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BT
98.784 451.51 Td
[<2843292051>5 <2C2050>-3 <2C2052>-2 <2C2053>]TJ
ET
Q
q
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BT
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ET
EMC
Q
Q
q
305.96 445.75 239.57 16.56 re
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q
305.95 445.75 239.57 16.56 re
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BT
311.35 451.51 Td
[<2844>5 <292051>5 <2C2050>-3 <2C2053>-3 <2C2052>]TJ
ET
Q
q
305.95 445.75 239.57 16.56 re
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EMC
Q
Q
BT
/P <</MCID 28 >>BDC
54 434.95 Td
<20>Tj
EMC
/P <</MCID 29 >>BDC
0 -13.8 Td
<20>Tj
EMC
ET
q
59.4 357.28 33.99 60.87 re
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q
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BT
64.824 407.35 Td
<512E3431>Tj
ET
Q
q
59.4 357.29 33.984 60.864 re
W* n
BT
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88.464 407.35 Td
( )Tj
ET
Q
q
59.4 357.29 33.984 60.864 re
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BT
100.82 407.35 Td
( )Tj
ET
EMC
Q
Q
/P <</MCID 31 >>BDC
q
93.39 357.29 452.13 60.864 re
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BT
99.144 407.35 Td
[(C)-2 (a)4 (lcula)4 (te the)4 ( followin)-10 (g)10 ( int)-3 (e)4 (g)10 (r)-6 (a)4 (l )]TJ
ET
Q
q
93.39 357.29 452.13 60.864 re
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BT
254.33 407.35 Td
[(\(up to two de)-4 (c)4 (im)-3 (a)4 (l pl)-3 (a)4 (c)4 (e)4 (s\))]TJ
ET
Q
q
93.39 357.29 452.13 60.864 re
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BT
381.67 407.35 Td
( )Tj
ET
EMC
Q
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q
93.39 357.28 452.13 60.87 re
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BT
319.39 393.55 Td
( )Tj
ET
EMC
Q
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q
93.39 357.28 452.13 60.87 re
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BT
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<05EC>Tj
ET
Q
q
93.39 357.28 452.13 60.87 re
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BT
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246.29 376.73 Td
<123A>Tj
ET
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93.39 357.28 452.13 60.87 re
W* n
BT
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251.33 376.25 Td
<0754>Tj
ET
Q
q
93.39 357.28 452.13 60.87 re
W* n
BT
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<0D45>Tj
ET
Q
q
93.39 357.28 452.13 60.87 re
W* n
BT
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<0375>Tj
ET
Q
q
93.39 357.28 452.13 60.87 re
W* n
BT
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278.93 376.73 Td
<123B>Tj
ET
Q
q
93.39 357.28 452.13 60.87 re
W* n
BT
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283.97 376.73 Td
<123A>Tj
ET
Q
q
93.39 357.28 452.13 60.87 re
W* n
BT
/C2_0 12 Tf
289.01 376.25 Td
<0754>Tj
ET
Q
q
93.39 357.28 452.13 60.87 re
W* n
BT
/C2_0 12 Tf
298.25 376.25 Td
<0D45>Tj
ET
Q
q
93.39 357.28 452.13 60.87 re
W* n
BT
/C2_0 12 Tf
309.91 376.25 Td
<0373>Tj
ET
Q
q
93.39 357.28 452.13 60.87 re
W* n
BT
/C2_0 12 Tf
316.51 376.73 Td
<123B>Tj
ET
Q
q
93.39 357.28 452.13 60.87 re
W* n
BT
/C2_0 12 Tf
321.55 376.25 Td
<07400754>Tj
ET
Q
q
93.39 357.28 452.13 60.87 re
W* n
BT
/C2_0 12 Tf
338.59 376.25 Td
<0D4C>Tj
ET
Q
q
93.39 357.28 452.13 60.87 re
W* n
BT
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241.37 383.59 Td
<0B35>Tj
ET
Q
q
93.39 357.28 452.13 60.87 re
W* n
BT
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238.97 371.21 Td
<0B34>Tj
ET
Q
q
93.39 357.28 452.13 60.87 re
W* n
BT
347.59 376.25 Td
<20>Tj
ET
Q
q
93.39 357.28 452.13 60.87 re
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BT
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<5F5F5F5F5F5F5F5F5F>Tj
ET
Q
q
93.39 357.28 452.13 60.87 re
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BT
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ET
EMC
Q
/P <</MCID 34 >>BDC
q
93.39 357.28 452.13 60.87 re
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BT
319.39 360.29 Td
<20>Tj
ET
EMC
Q
BT
/P <</MCID 35 >>BDC
54 339.29 Td
<20>Tj
EMC
/P <</MCID 36 >>BDC
0 -13.8 Td
<20>Tj
EMC
ET
q
59.4 223.36 33.99 99.12 re
W* n
/P <</MCID 37 >>BDC
q
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BT
64.824 311.69 Td
<512E3432>Tj
ET
Q
q
59.4 223.37 33.984 99.12 re
W* n
BT
/TT1 12 Tf
88.464 311.69 Td
( )Tj
ET
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59.4 223.37 33.984 99.12 re
W* n
BT
100.82 311.69 Td
( )Tj
ET
EMC
Q
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/P <</MCID 38 >>BDC
q
93.39 223.37 452.13 99.117 re
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BT
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[(The)5 ( prob)3 (a)4 (bil)-3 (it)-13 (y)20 ( dist)-4 (ributi)-2 (on fo)3 (r a)7 ( )]TJ
ET
Q
q
93.39 223.37 452.13 99.117 re
W* n
BT
259.97 311.33 Td
[(discr)-5 (e)4 (te r)-4 (a)4 (ndom var)5 (iable)4 ( )]TJ
ET
Q
q
93.39 223.37 452.13 99.117 re
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BT
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<073A>Tj
ET
Q
q
93.39 223.37 452.13 99.117 re
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BT
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<20>Tj
ET
Q
q
93.39 223.37 452.13 99.117 re
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BT
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[<69732067>7 <6976656E206265>6 <6C6F772E>]TJ
ET
Q
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93.39 223.37 452.13 99.117 re
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BT
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ET
EMC
Q
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q
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BT
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<20>Tj
ET
EMC
Q
q
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q
247.85 280.13 35.16 14.04 re
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BT
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261.41 282.77 Td
<073A>Tj
ET
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247.85 280.13 35.16 14.04 re
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BT
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<20>Tj
ET
EMC
Q
Q
q
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q
283.49 280.13 26.544 14.04 re
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BT
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293.45 282.77 Td
<0373>Tj
ET
Q
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283.49 280.13 26.544 14.04 re
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BT
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<20>Tj
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EMC
Q
Q
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q
310.51 280.13 26.52 14.04 re
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320.47 282.77 Td
<0374>Tj
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337.51 280.13 26.52 14.04 re
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347.47 282.77 Td
<0375>Tj
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337.51 280.13 26.52 14.04 re
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364.51 280.13 26.52 14.04 re
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BT
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374.47 282.77 Td
<0376>Tj
ET
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364.51 280.13 26.52 14.04 re
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BT
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<20>Tj
ET
EMC
Q
Q
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f*
247.37 294.17 0.48 0.48 re
f*
247.85 294.17 35.16 0.48 re
f*
283.01 294.17 0.48 0.48 re
f*
283.49 294.17 26.544 0.48 re
f*
310.03 294.17 0.48 0.48 re
f*
310.51 294.17 26.52 0.48 re
f*
337.03 294.17 0.48 0.48 re
f*
337.51 294.17 26.52 0.48 re
f*
364.03 294.17 0.48 0.48 re
f*
364.51 294.17 26.52 0.48 re
f*
391.03 294.17 0.48 0.48 re
f*
391.03 294.17 0.48 0.48 re
f*
247.37 280.13 0.48 14.04 re
f*
283.01 280.13 0.48 14.04 re
f*
310.03 280.13 0.48 14.04 re
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337.03 280.13 0.48 14.04 re
f*
364.03 280.13 0.48 14.04 re
f*
391.03 280.13 0.48 14.04 re
f*
EMC
q
247.85 265.48 35.16 14.04 re
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q
247.85 265.49 35.16 14.04 re
W* n
BT
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253.01 268.25 Td
<0732>Tj
ET
Q
q
247.85 265.49 35.16 14.04 re
W* n
BT
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260.69 268.25 Td
<123A>Tj
ET
Q
q
247.85 265.49 35.16 14.04 re
W* n
BT
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265.73 268.25 Td
<073A>Tj
ET
Q
q
247.85 265.49 35.16 14.04 re
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BT
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273.77 268.25 Td
<123B>Tj
ET
Q
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247.85 265.49 35.16 14.04 re
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<20>Tj
ET
EMC
Q
Q
q
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q
283.49 265.49 26.544 14.04 re
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BT
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288.89 268.13 Td
<0372>Tj
ET
Q
q
283.49 265.49 26.544 14.04 re
W* n
BT
/C2_0 12 Tf
295.49 268.13 Td
<01E4>Tj
ET
Q
q
283.49 265.49 26.544 14.04 re
W* n
BT
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298.01 268.13 Td
<0375>Tj
ET
Q
q
283.49 265.49 26.544 14.04 re
W* n
BT
304.63 268.13 Td
<20>Tj
ET
EMC
Q
Q
q
310.52 265.48 26.52 14.04 re
W* n
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q
310.51 265.49 26.52 14.04 re
W* n
BT
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315.91 268.13 Td
<0372>Tj
ET
Q
q
310.51 265.49 26.52 14.04 re
W* n
BT
/C2_0 12 Tf
322.51 268.13 Td
<01E4>Tj
ET
Q
q
310.51 265.49 26.52 14.04 re
W* n
BT
/C2_0 12 Tf
325.03 268.13 Td
<0376>Tj
ET
Q
q
310.51 265.49 26.52 14.04 re
W* n
BT
331.63 268.13 Td
<20>Tj
ET
EMC
Q
Q
q
337.52 265.48 26.52 14.04 re
W* n
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q
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52.56 46.104 317.95 0.48 re
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369.08 35.79 172.01 9.12 re
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369.08 35.79 172.01 9.12 re
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/P <</MCID 3 >>BDC
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q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
152.3 704.74 Td
[(is )-292 (the )-287 (numbe)-7 (r )-286 (of )-286 (viable)4 ( )-289 (spor)-7 (e)4 (s, )]TJ
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT2 12 Tf
323.59 704.74 Td
(t)Tj
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
326.95 704.74 Td
( )Tj
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
333.43 704.74 Td
[(is )-292 (the )-287 (ti)-3 (me, )]TJ
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT2 12 Tf
399.91 704.74 Td
(k)Tj
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT2 8.04 Tf
405.19 703.78 Td
(d)Tj
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
409.27 704.74 Td
( )Tj
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
415.75 704.74 Td
[(is )-292 (the )-287 (r)]TJ
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
455.38 704.74 Td
[(a)4 (te )-287 (c)4 (onst)-2 (a)4 (nt )-291 (a)4 (n)-9 (d)-9 ( )]TJ
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
542.76 704.74 Td
[( )-9 ( )]TJ
ET
EMC
Q
/P <</MCID 7 >>BDC
q
0.29514 0 0 0.42639 99.16 671.12 cm
/GS0 gs
/TT0 8.04 Tf
0 TL/Fm1 Do
Q
EMC
/P <</MCID 8 >>BDC
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS1 gs
/TT0 12 Tf
120.38 683.14 Td
( )Tj
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
123.38 683.14 Td
[(is t)-4 (he)4 ( ra)7 (te of)5 ( c)4 (h)-9 (a)4 (n)-9 (g)10 (e)4 ( o)-9 (f v)-6 (iable)4 ( spore)6 (s.)]TJ
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
302.11 683.14 Td
( )Tj
ET
EMC
Q
/P <</MCID 9 >>BDC
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
99.144 660.34 Td
[(I)13 (f)-6 ( )]TJ
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT2 12 Tf
110.06 660.34 Td
(k)Tj
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT2 8.04 Tf
115.34 659.38 Td
(d)Tj
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
119.42 660.34 Td
( )Tj
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
122.42 660.34 Td
[(v)-9 (a)4 (lue is)-10 ( 1.0 mi)-3 (n)]TJ
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
199.37 664.9 Td
(-)Tj
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
202.01 664.9 Td
(1)Tj
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
206.09 660.34 Td
[(, th)-11 (e)4 ( ti)-3 (me \()5 (in)-11 ( mi)-3 (nutes\))4 ( )-9 (re)7 (qui)-11 (re)7 (d to )-11 (re)7 (du)-9 (c)4 (e)4 ( th)-11 (e)4 ( numbe)-7 (r)-6 ( of via)5 (bl)-11 (e)4 ( spor)-7 (e)4 (s)9 ( )]TJ
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
99.144 646.54 Td
[(fr)6 (om an init)-3 (ial va)4 (lue of)5 ( 1)-9 (0)]TJ
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
0.06 Tc 224.81 651.1 Td
(10)Tj
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
232.97 646.54 Td
( )Tj
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
235.85 646.54 Td
[(to a f)5 (inal va)4 (lue of)5 ( 1 is)-12 ( )]TJ
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
343.51 646.54 Td
[(\(up to two de)5 (c)4 (im)-3 (a)4 (l pl)-3 (a)4 (c)-5 (e)-5 (s\))]TJ
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
470.86 646.54 Td
( )Tj
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
473.86 646.54 Td
(_________)Tj
ET
Q
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
527.86 646.54 Td
( )Tj
ET
EMC
Q
/P <</MCID 10 >>BDC
q
93.39 629.73 452.13 157.95 re
W* n
BT
/GS0 gs
/TT0 12 Tf
99.144 632.74 Td
( )Tj
ET
EMC
Q
BT
/P <</MCID 11 >>BDC
/GS0 gs
/TT0 12 Tf
54 611.74 Td
( )Tj
EMC
/P <</MCID 12 >>BDC
0 -13.8 Td
( )Tj
EMC
ET
q
59.4 539.71 33.99 55.215 re
W* n
/P <</MCID 13 >>BDC
q
59.4 539.71 33.984 55.224 re
W* n
BT
64.824 584.14 Td
(Q.45)Tj
ET
Q
q
59.4 539.71 33.984 55.224 re
W* n
BT
/TT1 12 Tf
88.464 584.14 Td
( )Tj
ET
Q
q
59.4 539.71 33.984 55.224 re
W* n
BT
100.82 584.14 Td
( )Tj
ET
EMC
Q
Q
/P <</MCID 14 >>BDC
q
93.39 539.71 452.13 55.215 re
W* n
BT
99.144 584.14 Td
[(An )-37 (a)4 (que)4 (ous )-40 (solut)-4 (ion )-41 (c)4 (on)10 (taining)8 ( )-39 (6.8 )-39 (mg)8 (/)-11 (L)21 ( )-39 (of )-36 (a)4 (n )-39 (a)-5 (nti)-3 (biot)-3 (ic )-37 (is)7 ( )-39 (e)4 (xtra)5 (c)4 (ted )-37 (with )-41 (a)4 (m)-11 (y)20 (l )-41 (a)4 (c)4 (e)4 (tat)-9 (e)4 (. )-49 (I)13 (f)-6 ( )]TJ
ET
Q
q
93.39 539.71 452.13 55.215 re
W* n
BT
99.144 570.34 Td
[(the )-37 (pa)4 (rtiti)-4 (on )-39 (c)4 (oe)-5 (ff)6 (icie)4 (nt )-51 (of )-36 (the )-37 (a)4 (nti)-3 (biot)-3 (ic )-37 (is )-42 (170 )-49 (a)-5 (nd )-39 (the )-37 (ra)7 (ti)-3 (o )-39 (o)-9 (f )-36 (wa)6 (t)-11 (e)4 (r )-36 (to )-41 (s)-10 (olvent )-39 (is )-42 (85, )-39 (then )]TJ
ET
Q
q
93.39 539.71 452.13 55.215 re
W* n
BT
99.144 556.51 Td
[(the e)6 (x)-9 (tra)5 (c)4 (ti)-3 (on fa)7 (c)4 (tor is )]TJ
ET
Q
q
93.39 539.71 452.13 55.215 re
W* n
BT
209.69 556.51 Td
[(__)-9 (_______)]TJ
ET
Q
q
93.39 539.71 452.13 55.215 re
W* n
BT
263.81 556.51 Td
( )Tj
ET
EMC
Q
/P <</MCID 15 >>BDC
q
93.39 539.71 452.13 55.215 re
W* n
BT
99.144 542.71 Td
( )Tj
ET
EMC
Q
BT
/P <</MCID 16 >>BDC
54 521.71 Td
( )Tj
EMC
/P <</MCID 17 >>BDC
0 -13.8 Td
( )Tj
EMC
ET
q
59.4 422.11 33.99 82.8 re
W* n
/P <</MCID 18 >>BDC
q
59.4 422.11 33.984 82.8 re
W* n
BT
64.824 494.11 Td
(Q.46)Tj
ET
Q
q
59.4 422.11 33.984 82.8 re
W* n
BT
/TT1 12 Tf
88.464 494.11 Td
( )Tj
ET
Q
q
59.4 422.11 33.984 82.8 re
W* n
BT
100.82 494.11 Td
( )Tj
ET
EMC
Q
Q
/P <</MCID 19 >>BDC
q
93.39 422.11 452.13 82.797 re
W* n
BT
99.144 494.11 Td
[(A )-267 (mi)-3 (c)4 (robia)5 (l )-271 (stra)4 (in )-271 (is )-272 (c)-5 (ult)-3 (ure)7 (d )-269 (in )-271 (a)4 ( )-269 (100 )-279 (L)11 ( )-269 (sti)-4 (r)-6 (re)7 (d )-269 (f)-6 (e)4 (rme)5 (nte)-7 (r )-266 (for)6 ( )-269 (s)-10 (e)4 (c)4 (on)-9 (da)4 (r)-16 (y)20 ( )-269 (meta)4 (boli)-3 (te)-7 ( )]TJ
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
99.144 480.31 Td
[(produ)3 (c)4 (ti)-3 (on. )-59 (I)13 (f )-46 (the)-7 ( )-49 (spe)3 (c)4 (ifi)-10 (c)4 ( )-49 (ra)7 (te)-7 ( )-49 (of )-46 (ox)-19 (y)20 (ge)-5 (n )-49 (uptake)-3 ( )-49 (is )-52 (0.4 )-49 (h)]TJ
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
/TT0 8.04 Tf
374.59 484.87 Td
(-)Tj
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
/TT0 8.04 Tf
377.23 484.87 Td
(1)Tj
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
381.31 480.31 Td
( )Tj
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
384.91 480.31 Td
[(a)4 (nd )-49 (the )-47 (ox)-19 (y)20 (ge)4 (n)-9 ( )-59 (solub)-2 (il)-3 (it)-13 (y)30 ( )-49 (in )-51 (the)-7 ( )]TJ
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
99.144 466.51 Td
[(broth )-178 (is )-182 (8 )-179 (mg)8 (/)-11 (L)11 (, )-179 (then)-7 ( )-179 (the )]TJ
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
233.81 466.51 Td
[(volum)-3 (e)4 (tric)3 ( )-179 (mass )-179 (tr)-8 (a)4 (n)-9 (sfe)6 (r )-176 (c)4 (o)-9 (e)4 (ff)6 (i)-11 (c)4 (ient)]TJ
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
413.35 466.51 Td
( )Tj
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
418.54 466.51 Td
(\()Tj
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
/TT2 12 Tf
422.5 466.51 Td
(K)Tj
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
/TT2 8.04 Tf
430.54 465.55 Td
(L)Tj
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
/TT2 12 Tf
434.98 466.51 Td
(a)Tj
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
440.98 466.51 Td
(\))Tj
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
444.94 466.51 Td
( )Tj
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
450.22 466.51 Td
[(\(in )-178 (s)]TJ
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
/TT0 8.04 Tf
473.38 471.07 Td
(-)Tj
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
/TT0 8.04 Tf
476.02 471.07 Td
(1)Tj
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
-0.036 Tc 480.1 466.51 Td
(\) )Tj
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
489.22 466.51 Td
[(of )-176 (ox)-19 (y)20 (ge)4 (n)-9 ( )]TJ
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
99.144 452.71 Td
[(re)7 (quire)5 (d )-289 (to )-291 (a)4 (c)4 (hieve)6 ( )-289 (a)4 ( )-299 (max)-7 (im)-3 (um)8 ( )-289 (c)4 (e)4 (ll)-3 ( )-289 (c)4 (onc)4 (e)4 (ntra)5 (ti)-3 (on )-289 (of )-286 (12 )-289 (g)10 (/)-11 (L)21 ( )-289 (is )]TJ
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
439.18 452.71 Td
[(\(up )-286 (to )-291 (two )-289 (de)4 (c)4 (im)-3 (a)4 (l)8 ( )]TJ
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
542.76 452.71 Td
( )Tj
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
99.144 438.91 Td
[(plac)6 (e)4 (s\))]TJ
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
132.98 438.91 Td
( )Tj
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
135.98 438.91 Td
(_________)Tj
ET
Q
q
93.39 422.11 452.13 82.797 re
W* n
BT
190.13 438.91 Td
( )Tj
ET
EMC
Q
/P <</MCID 20 >>BDC
q
93.39 422.11 452.13 82.8 re
W* n
BT
99.144 425.11 Td
( )Tj
ET
EMC
Q
BT
/P <</MCID 21 >>BDC
54 404.11 Td
( )Tj
EMC
/P <</MCID 22 >>BDC
0 -13.8 Td
( )Tj
EMC
ET
q
59.4 318.28 33.99 69.03 re
W* n
/P <</MCID 23 >>BDC
q
59.4 318.29 33.984 69.024 re
W* n
BT
64.824 376.49 Td
(Q.47)Tj
ET
Q
q
59.4 318.29 33.984 69.024 re
W* n
BT
/TT1 12 Tf
88.464 376.49 Td
( )Tj
ET
Q
q
59.4 318.29 33.984 69.024 re
W* n
BT
100.82 376.49 Td
( )Tj
ET
EMC
Q
Q
/P <</MCID 24 >>BDC
q
93.39 318.29 452.13 69.024 re
W* n
BT
99.144 376.49 Td
[(I)13 (n )-29 (a)4 ( )-39 (c)4 (he)4 (most)-4 (a)4 (t, )-31 (the )-27 (fe)-2 (e)4 (d )-29 (flow)3 ( )-29 (ra)7 (te )-27 (a)4 (nd )-29 (c)4 (ult)-3 (ur)-6 (e)4 ( )-29 (volum)-3 (e)4 ( )-29 (a)4 (re)7 ( )-29 (100 )-29 (ml)-3 (/h )-31 (a)4 (nd )-29 (1.0 )-39 (L)21 (, )-29 (re)7 (sp)-10 (e)4 (c)4 (ti)-3 (ve)4 (l)-21 (y)20 (.)-9 ( )]TJ
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
99.144 362.69 Td
[(W)-5 (it)-3 (h )10 (g)10 (lucose)5 ( )10 (a)4 (s )9 (subst)-3 (ra)7 (t)]TJ
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
215.69 362.69 Td
[(e)-5 (, )10 (the )]TJ
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
244.49 362.69 Td
[(va)4 (lues )11 (of )]TJ
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
/TT2 12 Tf
290.81 362.69 Td
(\265)Tj
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
/TT2 8.04 Tf
297.77 361.73 Td
[(m)5.995 (a)-5.995 (x)]TJ
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
311.23 362.69 Td
( )Tj
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
314.11 362.69 Td
[(a)4 (nd )]TJ
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
/TT2 12 Tf
334.27 362.69 Td
(K)Tj
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
/TT2 8.04 Tf
342.31 361.73 Td
(s)Tj
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
345.43 362.69 Td
( )Tj
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
348.31 362.69 Td
[(a)4 (re)7 ( )10 (0.2 )10 (h)]TJ
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
/TT0 8.04 Tf
389.59 367.25 Td
(-)Tj
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
/TT0 8.04 Tf
392.23 367.25 Td
(1)Tj
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
396.31 362.69 Td
( )Tj
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
399.19 362.69 Td
[(a)4 (nd )10 (1 g)10 (/)-11 (L)11 (, re)7 (s)-10 (pe)4 (c)4 (ti)-3 (ve)4 (l)-21 (y)20 (. )10 (F)6 (o)-9 (r )13 (a)-5 ( )]TJ
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
99.144 348.89 Td
[(g)10 (lucose)-4 ( )-119 (c)4 (on)-9 (c)4 (e)4 (ntr)-8 (a)4 (ti)-3 (on )-119 (of)-6 ( )-119 (10 )-129 (g)10 (/)-11 (L)11 ( )-119 (in )-121 (th)-11 (e)4 ( )-119 (f)-6 (e)4 (e)4 (d, )-119 (th)-11 (e)4 ( )-129 (e)4 (ff)6 (luent )-119 (subst)-3 (r)-6 (a)4 (te )-127 (c)4 (onc)4 (e)-5 (ntra)5 (ti)-3 (on )-119 (\(in )-128 (g)10 (/)-11 (L)11 (\))-6 ( )]TJ
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
542.76 348.89 Td
( )Tj
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
99.144 335.09 Td
(is )Tj
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
110.18 335.09 Td
(_________)Tj
ET
Q
q
93.39 318.29 452.13 69.024 re
W* n
BT
164.18 335.09 Td
( )Tj
ET
EMC
Q
/P <</MCID 25 >>BDC
q
93.39 318.28 452.13 69.03 re
W* n
BT
99.144 321.29 Td
( )Tj
ET
EMC
Q
BT
/P <</MCID 26 >>BDC
54 300.29 Td
( )Tj
EMC
/P <</MCID 27 >>BDC
0 -13.8 Td
( )Tj
EMC
ET
q
59.4 226.48 33.99 57 re
W* n
/P <</MCID 28 >>BDC
q
59.4 226.49 33.984 57 re
W* n
BT
64.824 272.69 Td
(Q.48)Tj
ET
Q
q
59.4 226.49 33.984 57 re
W* n
BT
/TT1 12 Tf
88.464 272.69 Td
( )Tj
ET
Q
q
59.4 226.49 33.984 57 re
W* n
BT
100.82 272.69 Td
( )Tj
ET
EMC
Q
Q
/P <</MCID 29 >>BDC
q
93.39 226.49 452.13 56.997 re
W* n
BT
99.144 271.73 Td
[(Ma)3 (mm)-3 (a)4 (li)-3 (a)4 (n )-69 (c)4 (e)4 (ll)-3 (s )]TJ
ET
Q
q
93.39 226.49 452.13 56.997 re
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186.77 271.73 Td
[(in )-71 (a)4 (c)4 (ti)6 (ve)4 ( )-69 (g)10 (row)5 (th )-71 (pha)4 (s)-10 (e)4 ( )]TJ
ET
Q
q
93.39 226.49 452.13 56.997 re
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301.15 271.73 Td
[(we)6 (re)7 ( )-69 (se)-6 (e)4 (de)4 (d )-69 (a)4 (t )-71 (a)4 ( )-69 (de)4 (nsit)-14 (y)20 ( )-69 (of)]TJ
ET
Q
q
93.39 226.49 452.13 56.997 re
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BT
434.62 271.73 Td
( )Tj
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q
93.39 226.49 452.13 56.997 re
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438.46 271.73 Td
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93.39 226.49 452.13 56.997 re
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/C0_0 12 Tf
444.46 271.73 Td
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93.39 226.49 452.13 56.997 re
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451.06 271.73 Td
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93.39 226.49 452.13 56.997 re
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/TT0 8.04 Tf
0.06 Tc 463.06 276.29 Td
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93.39 226.49 452.13 56.997 re
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469.66 271.73 Td
[(c)4 (e)4 (ll)-3 (s/m)-4 (l. )-71 (Af)5 (ter)5 ( )]TJ
ET
Q
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93.39 226.49 452.13 56.997 re
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542.76 271.73 Td
( )Tj
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Q
q
93.39 226.49 452.13 56.997 re
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99.144 256.97 Td
[(72 )-39 (hours, )-37 (1)]TJ
ET
Q
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93.39 226.49 452.13 56.997 re
W* n
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/C0_0 12 Tf
153.74 256.97 Td
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93.39 226.49 452.13 56.997 re
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160.34 256.97 Td
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93.39 226.49 452.13 56.997 re
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/TT0 8.04 Tf
172.34 261.53 Td
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93.39 226.49 452.13 56.997 re
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176.3 256.97 Td
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93.39 226.49 452.13 56.997 re
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179.81 256.97 Td
[(c)4 (e)4 (ll)-3 (s/m)-4 (l )-31 (we)6 (re)7 ( )-39 (obtaine)4 (d. )-39 (The)5 ( )]TJ
ET
Q
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93.39 226.49 452.13 56.997 re
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317.71 256.97 Td
[(popu)-9 (lation )]TJ
ET
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93.39 226.49 452.13 56.997 re
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372.67 256.97 Td
[(doubli)-3 (ng)10 ( )-39 (ti)-3 (me )-37 (of )-36 (t)8 (he)4 ( )-39 (c)4 (e)4 (ll)-3 (s )-40 (in )-41 (hour)13 (s)9 ( )]TJ
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93.39 226.49 452.13 56.997 re
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99.144 243.29 Td
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93.39 226.49 452.13 56.997 re
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110.18 243.29 Td
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93.39 226.49 452.13 56.997 re
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237.41 243.29 Td
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93.39 226.49 452.13 56.997 re
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240.41 243.29 Td
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93.39 226.49 452.13 56.997 re
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294.53 243.29 Td
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93.39 226.48 452.13 57 re
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99.144 229.49 Td
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0 -13.83 Td
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59.4 80.31 33.99 111.36 re
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59.4 80.304 33.984 111.36 re
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64.824 180.86 Td
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59.4 80.304 33.984 111.36 re
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88.464 180.86 Td
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59.4 80.304 33.984 111.36 re
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100.82 180.86 Td
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93.39 80.31 452.13 111.35 re
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99.144 180.86 Td
[(Ye)6 (a)4 (st )-122 (c)4 (onv)-9 (e)4 (rt)]TJ
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93.39 80.31 452.13 111.35 re
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166.82 180.86 Td
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93.39 80.31 452.13 111.35 re
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171.5 180.86 Td
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93.39 80.31 452.13 111.35 re
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176.06 180.86 Td
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93.39 80.31 452.13 111.35 re
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212.69 180.86 Td
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93.39 80.31 452.13 111.35 re
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217.13 180.86 Td
[(to )-121 (e)4 (thanol )-119 (a)4 (nd )-129 (c)4 (a)4 (rbon)-6 ( )-119 (diox)-11 (ide )-117 (b)-9 (y)20 ( )-129 (g)10 (l)-11 (y)20 (c)-5 (ol)-21 (y)30 (sis)-3 ( )-129 (a)4 (s )-120 (p)-9 (e)4 (r )-116 (the )-127 (following )]TJ
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93.39 80.31 452.13 111.35 re
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99.144 167.06 Td
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93.39 80.31 452.13 111.35 re
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141.14 167.06 Td
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93.39 80.31 452.13 111.36 re
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99.144 153.26 Td
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93.39 80.31 452.13 111.36 re
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246.05 138.5 Td
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93.39 80.31 452.13 111.36 re
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/TT0 8.04 Tf
254.09 137.54 Td
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93.39 80.31 452.13 111.36 re
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258.17 138.5 Td
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93.39 80.31 452.13 111.36 re
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/TT0 8.04 Tf
-0.06 Tc 266.81 137.54 Td
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93.39 80.31 452.13 111.36 re
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274.85 138.5 Td
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93.39 80.31 452.13 111.36 re
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283.37 137.54 Td
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93.39 80.31 452.13 111.36 re
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287.45 138.5 Td
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93.39 80.31 452.13 111.36 re
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290.45 138.5 Td
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93.39 80.31 452.13 111.36 re
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302.35 138.5 Td
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93.39 80.31 452.13 111.36 re
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305.35 138.5 Td
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93.39 80.31 452.13 111.36 re
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319.27 137.54 Td
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93.39 80.31 452.13 111.36 re
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323.35 138.5 Td
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93.39 80.31 452.13 111.36 re
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331.99 137.54 Td
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93.39 80.31 452.13 111.36 re
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336.07 138.5 Td
[(OH)4 ( +)4 ( 2C)-2 (O)]TJ
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93.39 80.31 452.13 111.36 re
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/TT0 8.04 Tf
388.75 137.54 Td
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93.39 80.31 452.13 111.36 re
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/TT0 8.04 Tf
392.71 137.54 Td
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93.39 80.31 452.13 111.36 re
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99.144 124.7 Td
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93.39 80.31 452.13 111.36 re
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99.144 110.9 Td
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93.39 80.31 452.13 111.36 re
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271.85 110.9 Td
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93.39 80.31 452.13 111.36 re
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0.024 Tc 99.144 97.104 Td
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93.39 80.31 452.13 111.36 re
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107.18 97.104 Td
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93.39 80.31 452.13 111.36 re
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110.18 97.104 Td
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93.39 80.31 452.13 111.36 re
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237.41 97.104 Td
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93.39 80.31 452.13 111.36 re
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240.41 97.104 Td
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93.39 80.31 452.13 111.36 re
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294.53 97.104 Td
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93.39 80.31 452.13 111.36 re
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99.144 83.304 Td
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/P <</MCID 40 >>BDC
54 62.304 Td
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/Artifact <</Attached [/Top ]/Subtype /Header /Type /Pagination >>BDC
BT
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54 798.36 Td
[(G)5.995 (A)6.007 (T)13.993 (E )-3.993 (2)-6.007 (0)7.002 (1)-5.995 (8)7.002 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )2.45 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-3.01 ( )10.995 ( )-2.985 ( )-3.01 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-3.01 ( )-2.985 ( )10.983 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-3.01 ( )10.995 ( )-2.985 ( )-3.01 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )-52.04 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-3.01 ( )11.007 ( )-3.01 ( )-2.985 ( )10.995 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )10.995 ( )-3.01 ( )-2.985 ( )-3.01 ( )10.995 ( )-2.998 ( )-19.192 (B)-3.993 (i)-5 (o)6.99 (t)-5 (e)11.007 (c)10.995 (h)-5.995 (n)-6.007 (o)7.002 (l)9.005 (o)7.002 (g)-6.007 (y)3.321 ( )]TJ
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93.39 718.66 452.13 55.224 re
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99.144 749.26 Td
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93.39 718.66 452.13 55.224 re
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104.42 749.26 Td
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93.39 718.66 452.13 55.224 re
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542.76 749.26 Td
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93.39 718.66 452.13 55.224 re
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99.144 735.46 Td
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93.39 718.66 452.13 55.224 re
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110.18 735.46 Td
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93.39 718.66 452.13 55.224 re
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164.18 735.46 Td
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59.4 567.33 33.99 116.52 re
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59.4 567.34 33.984 116.52 re
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64.824 673.06 Td
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59.4 567.34 33.984 116.52 re
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88.464 673.06 Td
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100.82 673.06 Td
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93.39 567.34 452.13 116.51 re
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99.144 673.06 Td
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93.39 567.34 452.13 116.51 re
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145.46 673.06 Td
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93.39 567.34 452.13 116.51 re
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209.69 673.06 Td
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93.39 567.34 452.13 116.51 re
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212.81 673.06 Td
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93.39 567.34 452.13 116.51 re
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378.79 673.06 Td
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93.39 567.33 452.13 116.52 re
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93.39 567.33 452.13 116.52 re
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99.144 611.74 Td
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93.39 567.33 452.13 116.52 re
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214.49 611.74 Td
[(s)-10 (c)4 (oring )41 (sc)3 (he)4 (m)-11 (e)4 ( )40 (of )33 (a)4 (n )40 (ident)-9 (it)-13 (y)20 ( )40 (matr)3 (ix)-11 ( )40 (for)6 ( )40 (subst)-3 (it)-3 (uti)-3 (on, )40 (a)4 ( )30 (g)10 (a)4 (p )40 (in)]TJ
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93.39 567.33 452.13 116.52 re
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505.66 611.74 Td
[(it)-3 (iation )]TJ
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93.39 567.33 452.13 116.52 re
W* n
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99.144 597.94 Td
[(pe)4 (na)4 (lt)-13 (y)20 ( )-109 (of)-6 ( )-99 (1 )-109 (a)4 (nd )-99 (a)-5 ( )-109 (g)10 (a)4 (p)-9 ( )-99 (e)-5 (x)-9 (tension )-100 (pe)4 (na)4 (lt)-13 (y)20 ( )-99 (o)-9 (f )-96 (0.1,)-9 ( )-109 (the )-97 (sc)3 (or)-6 (e)4 ( )-99 (of)-6 ( )-99 (the)-7 ( )-99 (a)4 (li)-13 (g)10 (nme)-7 (nt )-101 (is )]TJ
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93.39 567.33 452.13 116.52 re
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488.62 597.94 Td
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93.39 567.33 452.13 116.52 re
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522.46 597.94 Td
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93.39 567.33 452.13 116.52 re
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99.144 584.14 Td
[(de)4 (c)4 (im)-3 (a)4 (l pl)-3 (a)4 (c)4 (e)]TJ
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93.39 567.33 452.13 116.52 re
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165.38 584.14 Td
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93.39 567.33 452.13 116.52 re
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169.34 584.14 Td
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q
93.39 567.33 452.13 116.52 re
W* n
BT
172.34 584.14 Td
[(________)-9 (_)]TJ
ET
Q
q
93.39 567.33 452.13 116.52 re
W* n
BT
226.49 584.14 Td
( )Tj
ET
EMC
Q
/P <</MCID 10 >>BDC
q
93.39 567.33 452.13 116.52 re
W* n
BT
99.144 570.34 Td
( )Tj
ET
EMC
Q
BT
/P <</MCID 11 >>BDC
54 549.31 Td
( )Tj
EMC
/P <</MCID 12 >>BDC
0 -13.8 Td
( )Tj
EMC
ET
q
59.4 491.12 33.99 41.4 re
W* n
/P <</MCID 13 >>BDC
q
59.4 491.11 33.984 41.4 re
W* n
BT
64.824 521.71 Td
(Q.52)Tj
ET
Q
q
59.4 491.11 33.984 41.4 re
W* n
BT
/TT1 12 Tf
88.464 521.71 Td
( )Tj
ET
Q
q
59.4 491.11 33.984 41.4 re
W* n
BT
100.82 521.71 Td
( )Tj
ET
EMC
Q
Q
q
93.39 491.12 452.13 41.4 re
W* n
/P <</MCID 14 >>BDC
q
93.384 491.11 452.14 41.4 re
W* n
BT
99.144 521.71 Td
[(F)6 (irst )-301 (orde)7 (r )-296 (d)]TJ
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
165.62 521.71 Td
[(e)4 (a)4 (c)4 (ti)-3 (va)4 (ti)-3 (on)-9 ( )-299 (ra)7 (te )-297 (c)4 (onst)-2 (a)4 (nts )-302 (for)6 ( )-299 (sol)-12 (uble )-297 (a)4 (nd )-299 (im)-3 (mobi)-3 (li)-3 (z)-5 (e)4 (d )-289 (a)4 (m)-11 (y)20 (lo)-11 (g)10 (lucosida)3 (s)-10 (e)4 ( )]TJ
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
99.144 507.91 Td
[(e)4 (nz)-15 (y)20 (me )]TJ
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
138.86 507.91 Td
[(a)4 (re)-2 ( )50 (0.03)]TJ
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
176.9 507.91 Td
( )Tj
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
0.024 Tc 179.3 507.91 Td
(min)Tj
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
/TT0 8.04 Tf
198.05 512.47 Td
(-)Tj
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
/TT0 8.04 Tf
200.69 512.47 Td
(1)Tj
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
204.77 507.91 Td
( )Tj
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
207.17 507.91 Td
[(a)4 (n)-9 (d )50 (0.005 )50 (mi)-3 (n)]TJ
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
/TT0 8.04 Tf
275.09 512.47 Td
(-)Tj
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
/TT0 8.04 Tf
277.73 512.47 Td
(1)Tj
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
281.81 507.91 Td
[(, )50 (re)7 (spe)3 (c)4 (ti)-3 (ve)4 (l)-11 (y)20 (.)-9 ( )50 (Th)-8 (e)4 ( )]TJ
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
371.59 507.91 Td
[(r)-6 (a)4 (ti)-3 (o )50 (of )]TJ
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
408.43 507.91 Td
(ha)Tj
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
0.144 Tc 419.74 507.91 Td
(lf)Tj
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
427.18 507.91 Td
(-)Tj
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
431.14 507.91 Td
[(li)-3 (fe)7 ( )50 (o)-9 (f)-6 ( )50 (the )52 (im)-3 (mobi)-3 (li)-3 (z)-5 (e)14 (d)10 ( )]TJ
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
99.144 494.11 Td
[(e)4 (nz)-15 (y)20 (me )]TJ
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
139.34 494.11 Td
(to )Tj
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
151.7 494.11 Td
[(that of)3 ( the sol)-10 (uble e)6 (nz)-15 (y)20 (me is)]TJ
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
289.37 494.11 Td
( )Tj
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
292.37 494.11 Td
(\()Tj
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
296.33 494.11 Td
[(round)-6 (e)4 (d )-9 (off)6 ( to t)-3 (he)4 ( ne)4 (a)-5 (re)7 (st i)-4 (nte)-7 (g)10 (e)4 (r)]TJ
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
456.1 494.11 Td
(\))Tj
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
460.18 494.11 Td
( )Tj
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
463.18 494.11 Td
(_________)Tj
ET
Q
q
93.384 491.11 452.14 41.4 re
W* n
BT
517.18 494.11 Td
( )Tj
ET
EMC
Q
Q
BT
/P <</MCID 15 >>BDC
54 473.11 Td
( )Tj
EMC
/P <</MCID 16 >>BDC
0 -13.8 Td
( )Tj
EMC
ET
q
59.4 373.48 33.99 82.83 re
W* n
/P <</MCID 17 >>BDC
q
59.4 373.49 33.984 82.824 re
W* n
BT
64.824 445.51 Td
(Q.53)Tj
ET
Q
q
59.4 373.49 33.984 82.824 re
W* n
BT
/TT1 12 Tf
88.464 445.51 Td
( )Tj
ET
Q
q
59.4 373.49 33.984 82.824 re
W* n
BT
100.82 445.51 Td
( )Tj
ET
EMC
Q
Q
/P <</MCID 18 >>BDC
q
93.39 373.49 452.13 82.824 re
W* n
BT
99.144 445.51 Td
[(C)-2 (onsi)-2 (de)4 (r )-36 (a)4 ( )-39 (sim)-4 (ple )-37 (uni)]TJ
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
205.61 445.51 Td
(-)Tj
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
209.57 445.51 Td
[(su)-10 (bstra)4 (te )-37 (e)4 (nz)-25 (y)30 (m)-11 (e)4 ( )-39 (that )-39 (follo)-10 (ws )-38 (Micha)5 (e)4 (li)-3 (s)]TJ
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
404.95 445.51 Td
(-)Tj
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
408.91 445.51 Td
[(Me)3 (nten)-7 ( )-39 (kinetics. )-38 (W)-5 (he)4 (n )-39 (the )]TJ
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
99.144 431.71 Td
[(e)4 (nz)-15 (y)20 (me )-117 (c)4 (a)4 (tal)-19 (y)30 (z)-15 (e)4 (d )-109 (re)-2 (a)4 (c)4 (ti)-13 (on )-109 (wa)6 (s )-110 (c)-5 (a)4 (rr)6 (ied)-7 ( )-109 (out )-111 (in )-111 (the )-107 (pre)7 (s)-10 (e)4 (nc)4 (e)4 ( )-109 (o)-9 (f )-106 (10 )-109 (nM )-120 (c)4 (o)-9 (nc)4 (e)4 (ntra)5 (ti)-3 (on )-109 (of )-116 (a)4 (n )]TJ
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
99.144 417.91 Td
[(inhi)-3 (bit)-3 (or, )-316 (ther)5 (e)4 ( )-319 (wa)6 (s )-320 (no )-319 (c)4 (ha)4 (nge)4 ( )-319 (in )-321 (the )-317 (max)-7 (i)8 (m)8 (a)4 (l )-321 (ve)4 (locit)-11 (y)20 (. )-319 (How)4 (e)4 (v)-9 (e)4 (r, )-316 (t)-11 (he)4 ( )-319 (slope )-318 (of )-316 (the)12 ( )]TJ
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
99.144 404.11 Td
[(L)11 (inew)-5 (e)4 (a)4 (v)-9 (e)4 (r)]TJ
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
155.66 404.11 Td
(-)Tj
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
159.74 404.11 Td
[(B)7 (urk )-46 (plot)]TJ
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
205.97 404.11 Td
( )Tj
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
209.57 404.11 Td
[(in)-11 (c)4 (re)7 (a)4 (s)-10 (e)4 (d )-49 (3)]TJ
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
264.53 404.11 Td
(-)Tj
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
268.49 404.11 Td
[(fold. )-48 (Th)-8 (e)4 ( )-49 (diss)-3 (oc)4 (iation )-51 (c)4 (onst)-2 (a)4 (nt )-51 (for)6 ( )-49 (the )-47 (e)-5 (nz)-15 (y)30 (m)-11 (e)]TJ
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
494.38 404.11 Td
(-)Tj
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
498.34 404.11 Td
[(inhi)-3 (bit)-3 (or )]TJ
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
99.144 390.31 Td
[(c)4 (ompl)-3 (e)4 (x)-9 ( )]TJ
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
143.54 390.31 Td
(\()Tj
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
147.5 390.31 Td
(in nM\) )Tj
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
183.53 390.31 Td
(is )Tj
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
194.57 390.31 Td
[(____)10 (_____)]TJ
ET
Q
q
93.39 373.49 452.13 82.824 re
W* n
BT
248.45 390.31 Td
( )Tj
ET
EMC
Q
/P <</MCID 19 >>BDC
q
93.39 373.48 452.13 82.83 re
W* n
BT
99.144 376.49 Td
( )Tj
ET
EMC
Q
BT
/P <</MCID 20 >>BDC
54 355.49 Td
( )Tj
EMC
/P <</MCID 21 >>BDC
0 -13.8 Td
( )Tj
EMC
ET
q
59.4 86.19 33.99 252.5 re
W* n
/P <</MCID 22 >>BDC
q
59.4 86.184 33.984 252.5 re
W* n
BT
64.824 327.89 Td
(Q.54)Tj
ET
Q
q
59.4 86.184 33.984 252.5 re
W* n
BT
/TT1 12 Tf
88.464 327.89 Td
( )Tj
ET
Q
q
59.4 86.184 33.984 252.5 re
W* n
BT
100.82 327.89 Td
( )Tj
ET
EMC
Q
Q
/P <</MCID 23 >>BDC
q
93.39 86.19 452.13 252.5 re
W* n
BT
99.144 327.89 Td
[(The)5 ( )-9 (produ)3 (c)4 (t )-11 (o)-9 (f )-6 (c)4 (ompl)-3 (e)4 (te)-7 ( )-19 (dig)8 (e)4 (sti)-4 (on )-9 (of )-6 (th)-11 (e)4 ( )-9 (plasmi)-2 (d )-19 (shown )-8 (be)4 (low )-9 (with )]TJ
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
/TT3 12 Tf
431.74 327.89 Td
[(Ec)5 (o)]TJ
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
450.34 327.89 Td
[(R)-12 (I )-6 (a)4 (nd )]TJ
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
/TT3 12 Tf
485.98 327.89 Td
(Hae)Tj
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
506.14 327.89 Td
[(II)6 (I)13 ( )-19 (wa)6 (s )]TJ
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
99.144 314.09 Td
[(purif)4 (ied )-297 (a)4 (nd )-299 (use)3 (d )-299 (a)4 (s )-300 (a)-5 ( )-299 (template)4 ( )-299 (in )-301 (a)4 ( )-299 (re)7 (a)4 (c)4 (ti)-3 (on )-299 (c)4 (ontaining)8 ( )-299 (Kle)4 (now )-297 (f)]TJ
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
451.3 314.09 Td
[(ra)-2 (g)10 (ment )-299 (of )-296 (DN)4 (A)-7 ( )]TJ
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
99.144 299.33 Td
[(pol)-11 (y)20 (mer)-4 (a)4 (se)3 (, )-249 (d)-9 (NT)3 (P)-3 (s )-250 (a)4 (nd)-9 ( )]TJ
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
226.25 299.33 Td
([)Tj
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
/C0_0 12 Tf
230.45 299.33 Td
<0044>Tj
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
237.77 299.33 Td
<2D>Tj
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
/TT0 8.04 Tf
0.06 Tc 241.73 303.89 Td
(32)Tj
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
249.89 299.33 Td
(P)Tj
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
256.61 299.33 Td
(])Tj
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
260.69 299.33 Td
(-)Tj
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
264.65 299.33 Td
[(dATP )-250 (in )-251 (a)4 ( )-249 (suit)-4 (a)4 (ble )-247 (re)-2 (a)4 (c)4 (ti)-3 (on )-249 (buf)-6 (fe)7 (r.)-6 ( )-249 (T)-8 (he)4 ( )-249 (produ)3 (c)4 (t)-11 ( )-249 (thus)7 ( )]TJ
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
99.144 285.65 Td
[(obtaine)4 (d wa)6 (s purif)3 (ied )-7 (a)4 (n)-9 (d subj)-2 (e)4 (c)4 (ted to ge)4 (l ele)-5 (c)4 (tro)-8 (phore)7 (sis)-3 ( followe)5 (d b)-19 (y)20 ( a)4 (ut)-11 (ora)7 (diogra)5 (ph)-19 (y)20 (. )]TJ
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
525.82 285.65 Td
( )Tj
ET
EMC
Q
/P <</MCID 24 >>BDC
q
93.39 86.19 452.13 252.5 re
W* n
BT
99.144 271.85 Td
( )Tj
ET
EMC
Q
/P <</MCID 25 >>BDC
q
93.39 86.19 452.13 252.5 re
W* n
BT
489.1 141.5 Td
( )Tj
ET
EMC
Q
/P <</MCID 26 >>BDC
q
93.39 86.19 452.13 252.5 re
W* n
BT
99.144 130.58 Td
( )Tj
ET
EMC
Q
/P <</MCID 27 >>BDC
q
93.39 86.19 452.13 252.5 re
W* n
BT
99.144 116.78 Td
( )Tj
ET
EMC
Q
/P <</MCID 28 >>BDC
q
93.39 86.19 452.13 252.5 re
W* n
BT
99.144 102.98 Td
[(The)5 ( number)5 ( of b)-6 (a)4 (nds t)-2 (ha)-5 (t wil)-3 (l appe)6 (a)4 (r on the)5 ( X)]TJ
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
323.47 102.98 Td
(-)Tj
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
327.43 102.98 Td
[(ra)-2 (y)20 ( )-9 (film i)-4 (s )]TJ
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
379.75 102.98 Td
(______)Tj
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
415.75 102.98 Td
(___)Tj
ET
Q
q
93.39 86.19 452.13 252.5 re
W* n
BT
433.78 102.98 Td
( )Tj
ET
EMC
Q
/P <</MCID 29 >>BDC
q
93.39 86.19 452.13 252.5 re
W* n
BT
99.144 89.184 Td
( )Tj
ET
EMC
Q
BT
/P <</MCID 30 >>BDC
54 68.184 Td
( )Tj
EMC
ET
/P <</MCID 31 >>BDC
q
87.6 567.36 463.56 116.52 re
W* n
q
69 0 0 47.52 284.88 622.56 cm
/Im0 Do
Q
EMC
Q
/P <</MCID 32 >>BDC
q
87.6 86.28 463.56 252.48 re
W* n
q
4.7117 0 0 1.77 149.76 141.48 cm
/TT0 12 Tf
0 TL/Fm0 Do
Q
EMC
Q
/Artifact <</Attached [/Top ]/Subtype /Header /Type /Pagination >>BDC
BT
/TT0 8.04 Tf
54 798.36 Td
[(G)5.995 (A)6.007 (T)13.993 (E )-3.993 (2)-6.007 (0)7.002 (1)-5.995 (8)7.002 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )2.45 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-3.01 ( )10.995 ( )-2.985 ( )-3.01 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-3.01 ( )-2.985 ( )10.983 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-3.01 ( )10.995 ( )-2.985 ( )-3.01 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )10.995 ( )-2.998 ( )-2.998 ( )-52.04 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-3.01 ( )11.007 ( )-3.01 ( )-2.985 ( )10.995 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )11.007 ( )-3.01 ( )-2.998 ( )10.995 ( )-3.01 ( )-2.985 ( )-3.01 ( )10.995 ( )-2.998 ( )-19.192 (B)-3.993 (i)-5 (o)6.99 (t)-5 (e)11.007 (c)10.995 (h)-5.995 (n)-6.007 (o)7.002 (l)9.005 (o)7.002 (g)-6.007 (y)3.321 ( )]TJ
ET
52.56 795 490.44 0.48 re
f*
EMC
/Artifact <</Attached [/Bottom ]/Subtype /Footer /Type /Pagination >>BDC
BT
0.0373 Tc 54 37.824Tj
0 Tc 10.224 0 Td
( )Tj
ET
52.56 46.104 317.95 0.48 re
f*
q
369.08 35.79 172.01 9.12 re
W* n
BT
0.06 Tc 522.82 37.704 Td
(12)Tj
ET
Q
q
369.08 35.79 172.01 9.12 re
W* n
BT
530.86 37.704 Td
(/)Tj
ET
Q
q
369.08 35.79 172.01 9.12 re
W* n
BT
-0.06 Tc 533.14 37.704 Td
(12)Tj
ET
Q
q
369.08 35.79 172.01 9.12 re
W* n
BT
541.08 37.704 Td
( )Tj
ET
EMC
Q
BT
/P <</MCID 0 >>BDC
/TT0 12 Tf
54 776.88 Td
( )Tj
EMC
/P <</MCID 1 >>BDC
0 -13.8 Td
( )Tj
EMC
ET
q
59.4 704.01 33.99 56.07 re
W* n
/P <</MCID 2 >>BDC
q
59.4 704.02 33.984 56.064 re
W* n
BT
64.824 749.26 Td
(Q.55)Tj
ET
Q
q
59.4 704.02 33.984 56.064 re
W* n
BT
/TT1 12 Tf
88.464 749.26 Td
( )Tj
ET
Q
q
59.4 704.02 33.984 56.064 re
W* n
BT
100.82 749.26 Td
( )Tj
ET
EMC
Q
Q
/P <</MCID 3 >>BDC
q
93.39 704.02 452.13 56.064 re
W* n
BT
99.144 749.26 Td
[(A )12 (rod )13 (sha)3 (pe)4 (d )10 (ba)-5 (c)4 (ter)5 (i)]TJ
ET
Q
q
93.39 704.02 452.13 56.064 re
W* n
BT
198.29 749.26 Td
(um)Tj
ET
Q
q
93.39 704.02 452.13 56.064 re
W* n
BT
213.65 749.26 Td
( )Tj
ET
Q
q
93.39 704.02 452.13 56.064 re
W* n
BT
216.65 749.26 Td
[(ha)4 (s )9 (a)4 ( )10 (len)-7 (g)10 (th )8 (of )13 (2 )10 (\265)-3 (m)]TJ
ET
Q
q
93.39 704.02 452.13 56.064 re
W* n
BT
314.59 749.26 Td
[(, )10 (diame)4 (ter)5 ( )10 (of )13 (1 )10 (\265)-3 (m )8 (a)4 (nd )]TJ
ET
Q
q
93.39 704.02 452.13 56.064 re
W* n
BT
426.34 749.26 Td
[(de)4 (nsit)-4 (y)20 ( )]TJ
ET
Q
q
93.39 704.02 452.13 56.064 re
W* n
BT
463.78 749.26 Td
(the )Tj
ET
Q
q
93.39 704.02 452.13 56.064 re
W* n
BT
481.3 749.26 Td
[(sa)3 (me a)6 (s )9 (that )]TJ
ET
Q
q
93.39 704.02 452.13 56.064 re
W* n
BT
99.144 735.46 Td
[(of )-46 (wa)6 (ter)5 (. )-69 (I)13 (f )-46 (prote)5 (ins )-52 (c)4 (ons)-10 (ti)-3 (tut)-3 (e)4 ( )-49 (15%)3 ( )-49 (of )-46 (the )]TJ
ET
Q
q
93.39 704.02 452.13 56.064 re
W* n
BT
307.51 735.46 Td
[(c)4 (e)4 (ll)-3 ( )]TJ
ET
Q
q
93.39 704.02 452.13 56.064 re
W* n
BT
328.39 735.46 Td
[(mass )-49 (a)4 (nd )-49 (the )-47 (a)4 (ve)4 (r)-6 (a)-5 (g)10 (e)4 ( )-49 (prote)5 (i)-11 (n )-49 (ha)4 (s )-50 (a)4 ( )-49 (mass )-49 (of)-6 ( )]TJ
ET
Q
q
93.39 704.02 452.13 56.064 re
W* n
BT
542.76 735.46 Td
( )Tj
ET
Q
q
93.39 704.02 452.13 56.064 re
W* n
BT
99.144 721.66 Td
[(50 kDa)6 (, the numbe)4 (r o)-6 (f pr)-3 (oteins)]TJ
ET
Q
q
93.39 704.02 452.13 56.064 re
W* n
BT
249.17 721.66 Td
( )Tj
ET
Q
q
93.39 704.02 452.13 56.064 re
W* n
BT
252.17 721.66 Td
[(in t)-3 (he)4 ( c)4 (e)4 (ll)-3 ( is)]TJ
ET
Q
q
93.39 704.02 452.13 56.064 re
W* n
BT
310.51 721.66 Td
( )Tj
ET
Q
q
93.39 704.02 452.13 56.064 re
W* n
BT
313.51 721.66 Td
(_________)Tj
ET
Q
q
93.39 704.02 452.13 56.064 re
W* n
BT
367.51 721.66 Td
( )Tj
ET
EMC
Q
/P <</MCID 4 >>BDC
q
93.39 704.01 452.13 56.07 re
W* n
BT
99.144 706.9 Td
[(\(1 D)5 (a)4 ( )]TJ
ET
Q
q
93.39 704.01 452.13 56.07 re
W* n
BT
129.02 706.9 Td
[(=)4 ( 1.6 )]TJ
ET
Q
q
93.39 704.01 452.13 56.07 re
W* n
BT
/C0_0 12 Tf
156.74 706.9 Td
<0075>Tj
ET
Q
q
93.39 704.01 452.13 56.07 re
W* n
BT
163.34 706.9 Td
<20>Tj
ET
Q
q
93.39 704.01 452.13 56.07 re
W* n
BT
166.34 706.9 Td
<3130>Tj
ET
Q
q
93.39 704.01 452.13 56.07 re
W* n
BT
/TT0 8.04 Tf
178.34 711.46 Td
(-)Tj
ET
Q
q
93.39 704.01 452.13 56.07 re
W* n
BT
/TT0 8.04 Tf
0.06 Tc 181.01 711.46 Td
(24)Tj
ET
Q
q
93.39 704.01 452.13 56.07 re
W* n
BT
-0.12 Tc 189.17 706.9 Td
(g\))Tj
ET
Q
q
93.39 704.01 452.13 56.07 re
W* n
BT
199.13 706.9 Td
( )Tj
ET
EMC
Q
BT
/P <</MCID 5 >>BDC
/TT2 12.96 Tf
297.77 684.7 Td
( )Tj
EMC
/P <</MCID 6 >>BDC
/TT0 11.04 Tf
-243.77 -12.84 Td
( )Tj
EMC
/P <</MCID 7 >>BDC
0 -12.6 Td
( )Tj
EMC
/P <</MCID 8 >>BDC
/TT2 12.96 Tf
144.77 -14.88 Td
[(END OF )-8.002 (THE )-6.998 (QUES)-6.998 (TION PA)-8.002 (PER)-16.057 ( )]TJ
EMC
ET
Q.No. Type Section Key/Range Marks
1 MCQ GA A 1
2 MCQ GA C 1
3 MCQ GA B 1
4 MCQ GA C 1
5 MCQ GA D 1
6 MCQ GA A 2
7 MCQ GA C 2
8 MCQ GA D 2
9 MCQ GA C 2
10 MCQ GA A 2
1 MCQ BT C 1
2 MCQ BT C 1
3 MCQ BT B 1
4 MCQ BT D 1
5 MCQ BT C 1
6 MCQ BT D 1
7 MCQ BT C 1
8 MCQ BT B 1
9 MCQ BT B 1
10 MCQ BT D 1
11 MCQ BT D 1
12 MCQ BT C 1
Q.No. Type Section Key/Range Marks
13 MCQ BT B 1
14 MCQ BT C 1
15 MCQ BT A 1
16 MCQ BT D 1
17 MCQ BT B 1
18 MCQ BT B 1
19 MCQ BT C 1
20 MCQ BT B 1
21 NAT BT ‐10 to ‐10 1
22 NAT BT 0.32 to 0.32 1
23 NAT BT 50 to 50 1
24 NAT BT 1 to 11
25 NAT BT 4096 to 4096 1
26 MCQ BT D 2
27 MCQ BT A 2
28 MCQ BT D 2
29 MCQ BT C 2
30 MCQ BT A 2
31 MCQ BT B 2
32 MCQ BT C 2
33 MCQ BT C 2
34 MCQ BT B 2
Q.No. Type Section Key/Range Marks
35 MCQ BT C 2
36 MCQ BT D 2
37 MCQ BT A 2
38 MCQ BT C 2
39 MCQ BT D 2
40 MCQ BT C 2
41 NAT BT 5.30 to 5.34 2
42 NAT BT 2.1 to 2.1 2
43 NAT BT 2.25 to 2.25 2
44 NAT BT 23.02 to 23.04 2
45 NAT BT 2 to 22
46 NAT BT 0.16 to 0.17 2
47 NAT BT 1 to 12
48 NAT BT 21.00 to 22.00 2
49 NAT BT 102.00 to 103.00 2
50 NAT BT 600 to 600 2
51 NAT BT 1.8 to 1.9 2
52 NAT BT 6 to 62
53 NAT BT 5 to 52
54 NAT BT 2 to 22
55 NAT BT 2900000 to 3200000 2