GATE BT 2026 Question Paper & Solutions

Verbal Aptitude

"He often _____ the numbers. False claims are not going to help. Honesty _____ trust", said the manager. Choose the option with the correct order of words to fill the blanks.

Quantitative & Analytical Aptitude

In the sequence of tiles shown below, the missing tile indicated by the question mark should be (A) (B) (C) (D)

Quantitative & Analytical Aptitude

A school has 100 students distributed among 1st to 10th standards. Based on this, which one of the following statements is always correct?

Quantitative & Analytical Aptitude

How many 3-digit numbers can be formed using three distinct single digit prime numbers?

Quantitative & Analytical Aptitude

In a group of students, 10 students like Mathematics, 12 students like English, 4 students like both Mathematics and English, and 6 students like neither Mathematics nor English. The number of students in the group is ____

Verbal Aptitude

Charity : P :: Retaliation : Q Choose the appropriate pair of words P and Q that fit the analogy.

Quantitative & Analytical Aptitude

A paper shown in Panel I is folded along the dashed lines (- - -) to construct a cube. The shaded regions shown in Panel I appear on the outer surface of the cube. Referring to cubes shown in Panel II, which one of the options is correct?

Quantitative & Analytical Aptitude

Consider the cube shown below with its 8 corners labelled a, b, c, d, e, f, g, and h. The figure is representative. All corners are to be colored such that any two corners that are connected by an edge must be of different colors. The minimum number of colors required to achieve this is ________

Quantitative & Analytical Aptitude

Four hills H1, H2, H3, and H4 are present in an area. The following observations are made about them: i. Neither H2 nor H3 is the easternmost hill. ii. Neither H2 nor H3 is the westernmost hill. iii. Neither the easternmost hill nor the westernmost hill is the southernmost hill. iv. Two hills are located to the west of H2. v. The southernmost hill has at least two hills to its east. The southernmost hill is ________.

Quantitative & Analytical Aptitude

As shown in the figure, circle C1 with center O1 and radius r1 touches the square VWXY at points P and Q while circle C2 with center O2 and radius r2 touches the square VWXY at points R and S. The two circles touch each other at T. Given r1 = 1 cm and VY̅̅̅̅ = VW̅̅̅̅̅ = 4 cm, r2 = _____ cm.

Biochemistry, Microbiology & Molecular Biology

Consider the two functions f1(x) = x2-4 x-2 and f2(x) = x2 - 2x + 2. Which of the following is the value of (f1(x) + f2(x)) as x → 2 ?

Engineering Mathematics

Which of the following is one of the eigenvalues for the matrix given below? [3 4 4 -3]

Biochemistry, Microbiology & Molecular Biology

Which of the following functions has the highest area under the curve between x = 0 and x = 10?

Biochemistry, Microbiology & Molecular Biology

Cancer cells display a high level of heterogeneity in the expression of TP53 protein. Which of the following techniques can be directly used to determine the intra - tumoral heterogeneity of TP53 expression in a given tumor sample , without resorting to additional cell separation techniques?

Biochemistry, Microbiology & Molecular Biology

The transfer function of a Proportional-Integral (PI) controller GC(s) is given by GC(s) = KC (1 + 1 𝜏Is) where KC is the controller gain, 𝜏I is the controller integral time constant and s is the Laplace variable. The role of the integral component of the controller is to ____________.

Biochemistry, Microbiology & Molecular Biology

Which of the following enzyme is involved in the protection of cells from reactive oxygen species?

Biochemistry, Microbiology & Molecular Biology

In nitrogen fixation, to reduce nitrogen to ammonia , which one of the following shows the correct order of electron flow?

Cellular & Applied Biotechnology

For monoclonal antibody production, hypoxanthine ____________.

Bioprocess Engineering

Which one of the following proteins would elute third in gel filtration chromatography from a mixture of four proteins given below?

Biochemistry, Microbiology & Molecular Biology

Which one of the following antibiotics blocks protein chain elongation by preventing the action of peptidyl transferase ?

Biochemistry, Microbiology & Molecular Biology

The catalytic efficiency of an enzyme following Michaelis -Menten kinetics is defined by

Recombinant DNA Technology

The RNA primer synthesized during bacterial DNA replication is removed by ________.

Biochemistry, Microbiology & Molecular Biology

Match the carbohydrates in Column I with the correct glycosidic linkages involved in Column II. Column I Column II P. Amylose 1. β (1 4) Q. Sucrose 2. α (1 4) R. Amylopectin 3. α1 β2 S. Cellulose 4. α (1 4), α (1 6)

Biochemistry, Microbiology & Molecular Biology

The correct sequence of the four steps involved in anaerobic production of biogas from complex organics is:

Biochemistry, Microbiology & Molecular Biology

Which one of the following options represents the products of light reactions of photosynthesis in plants?

Recombinant DNA Technology

Which component of the CRISPR/Cas9 gene editing system is NOT of natural origin?

Biochemistry, Microbiology & Molecular Biology

The equation d2y dx2 - y = 0 has a solution of the form y = e Ax. The value(s) of A satisfying this is/are:

Biochemistry, Microbiology & Molecular Biology

Which of the following drugs inhibit(s) ATP-ADP translocase?

Engineering Mathematics

Which of the following is/are extra-cellular matrix protein(s)?

Biochemistry, Microbiology & Molecular Biology

BLAST and its extensions can be used to determine similarity of a query protein sequence with which of the following database(s)?

Biochemistry, Microbiology & Molecular Biology

The mean of the following series is ______. (rounded off to three decimal places) 0.01, 0.02, 0.03, ⋯ ⋯ , 1

Biochemistry, Microbiology & Molecular Biology

You are characterizing a new enzyme isolated and purified in the laboratory. If the maximum v elocity of the enzyme is 18 00 µmoles L -1 min-1 and the total concentration of the enzyme in the reaction mixture is 1.5 µM, then the turnover number of the enzyme is _______ s-1. (answer in integer)

Biochemistry, Microbiology & Molecular Biology

Question 33 from official GATE BT 2026 Examination.

Biochemistry, Microbiology & Molecular Biology

Given below is the Gibbs free energy change (ΔG) in kilo Joules per electron equivalent (kJ e-eq-1) at pH 7.0, of organic and inorganic half reactions. Acetate synthesis: 1 8 CO2 + 1 8 HCO3 - + H+ + e- → 1 8 CH3COO- + 3 8 H2O ΔG=27.4 kJ e-eq-1 Reduction reaction: 1 4 O2 + H+ + e- → 1 2 H2O ΔG= -78.72 kJ e-eq-1 The free energy change of acetate oxidation to CO2, H2O and HCO3 - is _______ kJ e-eq-1. (rounded off to two decimal places)

Biochemistry, Microbiology & Molecular Biology

You have purified an enzyme using a series of chromatographic methods. It was observed that a 10 µg mL-1 of this purified enzyme converted 10 mM substrate per hour at 25°C and pH 7. Its specific activity is _______ IU µg -1. (rounded off to three decimal places)

Biochemistry, Microbiology & Molecular Biology

In the open-loop process shown in the figure, the input U(s), the transfer function Gp(s) and the output Y(s) are given in the Laplace domain in terms of the Laplace variable s. For this process, which of the following is true? (where M, 𝜏p, KP, are the magnitude of the input, the characteristic time and the gain for the process, respectively)

Cellular & Applied Biotechnology

Match the immunological terms in Column I with their function/description in the Column II Column I Column II P. J gene 1. Suppresses immune system by blocking calcineurin Q. Cyclosporin 2. Antibody binding site on a large molecule R. Epitope 3. Small foreign molecule which elicits an immune response only when combined with a carrier molecule S. Hapten 4. Contributes to antibody diversity

Biochemistry, Microbiology & Molecular Biology

Match the genetic disorders in Column I to the corresponding underlying cause in Column II Column I Column II P. Klinefelter Syndrome 1. X-chromosome insufficiency Q. Turner syndrome 2. DNA helicase mutations R. Bloom syndrome 3. Nucleotide excision repair defects S. Xeroderma pigmentosum 4. Extra X chromosome(s) in a male

Biochemistry, Microbiology & Molecular Biology

Match the biomolecules in Column I with their function given in Column II Column I Column II P. Lectins 1. Acts as ATP dependent pump to efflux out small molecules Q. P-glycoprotein 2. Targets lysosomal enzymes to their destination R. Digitoxigenin 3. Specific carbohydrate binding proteins S. Mannose 6-phosphate 4. Inhibits Na+-K+ pump

Biochemistry, Microbiology & Molecular Biology

By elemental analysis of a biomass sample, it was found that the cells in the given sample are composed of (by weight) C=50 %, H=8%, O=20%, N=10% and ash content=12%. Which of the following is the correct empirical formula of the ash- free cells, normalized with respect to Nitrogen?

Engineering Mathematics

For the given matrix, which of the statements given below is/are true? [ 3 1 5 2 -1 0 5 2 9 ]

Biochemistry, Microbiology & Molecular Biology

Messenger RNAs (mRNAs) translate to generate polypeptides and the translation terminates at the UGA, UAG or UAA stop codons. The AGA codon acts as additional stop codon in the mitochondria. The longest possible polypeptide(s) that can be hypothetically translated in the cytosol and/or mitochondria, from the given full length mRNA sequence (36 nucleotides) is/are 5'-AACACCAUGACCCAUGUGGCGAGACGGUAGUUAAAA- 3'

Biochemistry, Microbiology & Molecular Biology

The RNA sequence below depicts the part of a 330 nucleotides long mRNA and it encodes the C-terminal portion of a protein. 5'-… … … AAC ACC ACG ACC CAU GUG GCG AGA CGG UAG- 3' A mutation was identified in this RNA denoted as 322A U. This nucleotide change is represented by which of the following class(es) of mutation?

Bioprocess Engineering

A microbial culture is being grown in a bioreactor with continuous aeration. The dissolved oxygen probe provided with the system shows a reading of zero. In this context, which of the following inferences is/are correct?

Biochemistry, Microbiology & Molecular Biology

For a Newtonian fluid, a plot of shear stress (on Y axis) against shear rate (on X axis) will result in a straight line ________.

Biochemistry, Microbiology & Molecular Biology

In an aerobic fermentation with air sparging, which of the following options can be used to increase the volumetric mass transfer coefficient for oxygen transfer?

Biochemistry, Microbiology & Molecular Biology

For a liquid flowing in a circular cross section pipe, the transition from laminar to turbulent flow will NOT depend on which of the following factor(s)?

Biochemistry, Microbiology & Molecular Biology

Which of the following is/are posttranslational modification(s) involved in epigenetic control of gene expression?

Biochemistry, Microbiology & Molecular Biology

For an ideal plug flow reactor, which of the following statements is/are true?

Biochemistry, Microbiology & Molecular Biology

An enzyme-catalyzed reaction is found to have ∆G = -100 kJ mol-1. Which of the following statements about this reaction is/are true?

Biochemistry, Microbiology & Molecular Biology

Consider the equation dy dx = 1 x The value of the integral ∫ dy 2 1 using trapezoidal method and interval ℎ = 0.25 is ________. (rounded off to two decimal places)

Biochemistry, Microbiology & Molecular Biology

If the straight lines given by the following two equations are parallel to each other, the value of a is _____. (answer in integer) 4x + 7y = 6; 3𝒂x + 42y = 24

Biochemistry, Microbiology & Molecular Biology

A straight line y = x - 1 intersects a circle with center at x = 1, y = 1 and radius of magnitude 1 at two points. The length of the chord formed by this intersection is _______. (rounded off to three decimal places)

Biochemistry, Microbiology & Molecular Biology

A heat exchanger during operation in a bioprocess has a steady temperature of 90 oC. After completion of its operation, it was shut down and it was observed that the rate of decrease of temperature at any time was directly proportional to the difference T(t) - 30 oC, where T(t) denotes temperature at time t. It was observed that it took 30 min for the temperature to drop to 70 oC. The temperature after 51.5 min will be_________ oC. (rounded off to the nearest integer)

Bioprocess Engineering

A microbial culture (following Monod model for growth) has a maximum specific growth rate of 0.1 h -1, Monod constant of 1 mg L -1 and endogenous decay rate of 0.1 day-1. At limiting substrate concentration of 23 g L-1, the net specific growth rate will be ________day-1. (rounded off to one decimal place)

Biochemistry, Microbiology & Molecular Biology

A CSTR with a volume of 100 m3 is operated in cell recycle mode. At a volumetric flow rate of 10 m3 day-1 and effluent biomass of 20 mg L-1, the steady state biomass concentration is 200 mg L-1. The mean cell retention time in the reactor is ____ days. (answer in integer)

Biochemistry, Microbiology & Molecular Biology

The electron equivalent per liter (e -eq L-1) of acetate ion solution of concentration 10 g L-1 is _______ e-eq L-1. (rounded off to one decimal place)

Biochemistry, Microbiology & Molecular Biology

From the following plot of dy dx versus x and if y(2) = 5, the value of y(3) is ________. (rounded off to one decimal place)

Cellular & Applied Biotechnology

A batch sterilizer is being operated at 121 oC for sterilizing a medium containing microbial cells. Assume that the thermal deactivation of cells is a first order process with a death rate constant of 0.69 min-1 at 121 oC. If the initial concentration of microbes in the medium is 1010 cells m-3, the time taken to reduce the microbial load to a final concentration of 10 cells m-3 is _________ min. (rounded off to the nearest integer)

Biochemistry, Microbiology & Molecular Biology

A substrate is consumed in a zero order reaction such that its concentration falls from 42 g L-1 to 14 g L-1 in 4 hours. The total time taken for complete utilization of substrate will be ________ hours. (answer in integer)

Bioprocess Engineering

A microbe that follows Monod growth kinetics on a limiting substrate (maximum specific growth rate of 0.5 h -1 and Monod constant of 0.1 mg L-1) is cultivated in a continuous reactor for microbial growth (chemostat) with sterile feed. Given that the chemostat volume is 5 L and inlet concentration of limiting substrate is 10 g L-1, the minimum inlet feed flow rate for chemostat washout is ______ L h-1. (rounded off to one decimal place)

Cellular & Applied Biotechnology

It is desired to cultivate 150 mg (dry weight) microbial cells with an empirical formula of C 5H7O2N. If the phosphorus requirement for the cells is 20% of the nitrogen requirement (on a weight/weight basis), the minimum amount of phosphorous required to be added to the cultivation medium is ________ mg. (rounded off to one decimal place) 0 1 2 3 4 0 1 2 3 x

Biochemistry, Microbiology & Molecular Biology

In the process of generating a clonal mammalian cell line, a single cell was seeded in a well of a cell culture plate. After the first 48 hours, one of the progeny cells underwent apoptosis due to a new mutation. If the doubling time of the cells is 24 hours and no more cell death occurs, the total number of cells after a total of 7 days from seeding will be ______. (answer in integer)

Engineering Mathematics

A disease-associated allele shows X-linked recessive inheritance. If the mother is a carrier of the disease, the father is genetically normal and the child born is a son, then the probability that he is born with the disease is _______. (rounded off to one decimal place)

Bioprocess Engineering

A packed bed bioreactor with length 1 m and inside diameter 10 cm has liquid flowing at an interstitial velocity of 1 cm s -1. Given a volumetric flow rate of 0.025 L s -1, the void frac tion of the packed bed is _____ _. ( rounded off to two decimal places) END OF QUESTION PAPER